Results 71 to 80 of about 87,634 (287)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Bringing America Up to Speed: States' Role in Expanding Broadband [PDF]
, 2010 Describes innovative state programs to expand access to high-quality, high-speed broadband; the National Broadband Plan -- a partnership of state, federal, and local governments; providers; and nonprofits -- and roles and challenges for ...
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Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
No caçar dos erros, a língua que escapa
Cadernos de Estudos Lingüísticos, 2018 Este artigo, ancorado na Análise do Discurso pêcheuxtiana, objetiva analisar o funcionamento dos dizeres sobre o revisor de textos da publicidade a partir de um corpus experimental, que consta de entrevistas com sujeitos envolvidos na etapa de revisão do
Debbie Mello Noble
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
En efterfrågestyrd revision -Behovet av anpassade standarder för revision av mindre företag utifrån revisorns perspektiv [PDF]
, 2017 Bakgrund och problem: Revisorer har uttryckt att det nuvarande revisionsregelverket (ISA) har blivit alltför omfattande, komplext och otympligt vid revision av mindre företag.
Gillmert, Axel, Persson, Henrik
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Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source