Results 101 to 110 of about 184,287 (297)

Macrophage–Derived Ferritin Exacerbates Silica‐Induced Pulmonary Fibrosis via PIK3R2‐Mediated Fibroblast Differentiation

open access: yesAdvanced Science, EarlyView.
This study identifies ferritin as a pivotal mediator of silica‐induced pulmonary fibrosis. Macrophage‐derived ferritin drives fibroblast‐to‐myofibroblast differentiation via the PIK3R2/SMAD pathway, while ferritin knockdown alleviates fibrosis. These findings define ferritin as both a biomarker and pathogenic driver, highlighting ferritin‐PIK3R2 ...
Liqun Wang   +14 more
wiley   +1 more source

Practices, Challenges, and Future of Digital Transformation in Smallholder Agriculture: Insights from a Literature Review

open access: yesAgriculture
Smallholder farmers play a crucial role in global agricultural development. The digital transformation of smallholder agriculture can enhance productivity, increase farmers’ income, ensure food security, and promote sustainable rural development. However,
Yuyang Yuan, Yong Sun
doaj   +1 more source

Lightside Atmospheric Revitalization System [PDF]

open access: yes
The system was studied as a replacement to the present baseline LiOH system for extended duration shuttle missions. The system consists of three subsystems: a solid amine water desorbed regenerable carbon dioxide removal system, a water vapor ...
Colling, A. K.   +3 more
core   +1 more source

Culture and Urban Revitalization: A Harvest Document [PDF]

open access: yes, 2007
Advocates have long argued that the economic benefits of the arts and culture provide a firm rationale for public support. Recent scholarship on the "creative class" and "creative economy" is simply the latest effort to link cultural expression to ...
Mark J. Stern, Susan C. Seifert
core  

Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma

open access: yesAdvanced Science, EarlyView.
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian   +7 more
wiley   +1 more source

Spatial–Temporal Coupling Characteristics and Interactive Effects of New-Type Urbanization and Cultivated Land Use Efficiency on Food Security

open access: yesAgriculture
Against the backdrop of rapid modernization and tightening agricultural resource constraints, coordinating urbanization and grain production is a key challenge for China.
Yihan Zhao   +3 more
doaj   +1 more source

Form follows experience: the revitalization of postindustrial sites by carnivalesque [PDF]

open access: yes, 2017
Recent decades are the times for intense socio-economic changes that have significantly influenced the forms of modern shaped public spaces. Freed brownfield sites, prior to transformation are spatial barriers by not integrated communication systems and ...
Szewczyk, Anna Faustyna
core   +1 more source

Identification of Mannose‐Capped‐Arabinomannan 101‐mer as a Potential Influenza Virus Vaccine Adjuvant

open access: yesAdvanced Science, EarlyView.
Well‐defined and synthetic mannose‐capped arabinomannan 101‐mer from Mycobacterium tuberculosis cell wall was identified as a potent influenza vaccine adjuvant, boosting the antibody response, realizing full protection and showing excellent safety. ABSTRACT Many natural bacterial components as adjuvants can activate the host immune system, but the ...
Yu‐Fang Zhang   +5 more
wiley   +1 more source

YOLOv8-MU: An Improved YOLOv8 Underwater Detector Based on a Large Kernel Block and a Multi-Branch Reparameterization Module

open access: yesSensors
Underwater visual detection technology is crucial for marine exploration and monitoring. Given the growing demand for accurate underwater target recognition, this study introduces an innovative architecture, YOLOv8-MU, which significantly enhances the ...
Xing Jiang   +4 more
doaj   +1 more source

Development Potentials For Palestine [PDF]

open access: yes, 2004
The author discusses issues surrounding the potential economic development of Palestine.
Rothermel, Timothy
core   +1 more source

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