Results 151 to 160 of about 188,445 (317)
Arthritis &Rheumatology, EarlyView.Objective This study aimed to investigate the mechanisms of immune dysregulation in a pediatric patient with monogenic lupus driven by IKZF1 haploinsufficiency. Methods Peripheral immune cells from a patient with IKZF1 haploinsufficiency, patients with lupus with no currently known genetic mutations, and healthy controls were analyzed using single‐cell
Qi Zheng +6 more
wiley +1 more source
Extended mission life support systems [PDF]
, 1985 Extended manned space missions which include interplanetary missions require regenerative life support systems. Manned mission life support considerations are placed in perspective and previous manned space life support system technology, activities and ...
Quattrone, P. D.
core +1 more source
Opposing consensus science through scholarly practices: The role of claims maintenance
Journal of the Association for Information Science and Technology, EarlyView.Abstract This study examines how three US‐based communities who oppose consensus science produce and disseminate scholarly‐like artifacts: pro‐life activists, Young Earth Creationists, and Anthropogenic Climate Crisis skeptics. Prior research shows that industry‐ or church‐backed advocacy campaigns often generate claims supported by these communities ...
Irene V. Pasquetto +3 more
wiley +1 more source
COMMODITY PROGRAMS AND RURAL REVITALIZATION [PDF]
Community/Rural/Urban Development,
Collins, Keith J., Vertrees, James G.
core +1 more source
Are HOPE VI Families at Greater Risk for Homelessness? [PDF]
, 2007 Examines whether federal HOPE VI relocation initiatives increase the chances that original residents will be at greater risk of homelessness.
Debi McInnis +2 more
core
Journal of the Association for Information Science and Technology, EarlyView.Abstract Online technologies are required for accessing essential services, such as healthcare, transportation, and education. Challenges to online technology access can prevent resource‐constrained communities from connecting to these services. Human intermediaries who act in the middle space between technology and the person using the technology may ...
Marcy G. Antonio +4 more
wiley +1 more source
Arthroscopy Techniques, EarlyView.Abstract Lateral extra‐articular tenodesis has emerged as a valuable adjunct to anterior cruciate ligament reconstruction for mitigating residual rotational instability. We describe a modified lateral extra‐articular tenodesis technique utilizing an all‐suture knotless anchor with suture tape, which provides strong, flexible fixation with reduced soft ...
Bryson R. Kemler +2 more
wiley +1 more source
Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi +1 more
wiley +1 more source
Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients
British Journal of Clinical Pharmacology, EarlyView.Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel +12 more
wiley +1 more source