Results 101 to 110 of about 593,600 (333)

Semi-dynamical approach to the shock revival in core-collapse supernovae

, 2013
We develop a new semi-dynamical method to study shock revival by neutrino heating in core- collapse supernovae. Our new approach is an extension of the previous studies that employ spherically symmetric, steady, shocked accretion flows together with the ...
Blondin, Bruenn, Burrows, Burrows, Dolence, Fernández, Foglizzo, Hanke, Hiroki Nagakura, Iwakami, Marek, Mueller, Murphy, Murphy, Murphy, Nagakura, Nagakura, Nagakura, Nagakura, Nakayama, Nakayama, Nobuta, Nordhaus, Ohnishi, Ott, Pejcha, Shen, Shoichi Yamada, Suwa, Takiwaki, Yamamoto, Yamasaki, Yamasaki, Yu Yamamoto   +33 more
core   +1 more source

Engineered Mesenchymal Stem Cell–NK Cell Complexes for Spatially Targeted and Functionally Revitalized Cancer Immunotherapy

Advanced Science, EarlyView.
IL‐15‐engineered stem cell–NK cell complexes, assembled via bioorthogonal chemistry, enable effective lung cancer immunotherapy. Abstract Natural killer (NK) cells represent a powerful immunotherapeutic strategy due to their intrinsic cytotoxicity and ability to target tumor cells independently of antigen presentation.
Qian Zhang, Bo Yin, Munaiwaier Sabier, Youlan Yang, Mengling Wu, Zhouping Zhao, Xuanzhi Luo, Yuehong Zhong, Xiuming Zhu, Jie Zhang, Jing Wang, Kai Chen, Fei Ruan, Wei Zhang, Zhimin Lu, Jiong Wang   +15 more
wiley   +1 more source

Global reversal, regional revival?

Transitions in Regional Economic Development, 2017
This is an Accepted Manuscript of an article published by Taylor & Francis in Regional Studies on 19 January 2017, available online: http://www.tandfonline.com/10.1080/00343404.2016.1255720.
I. Turok, David Bailey, Jennifer Clark, Jun Du, U. Fratesi, M. Fritsch, J. Harrison, T. Kemeny, D. Kogler, A. Lagendijk, T. Mickiewicz, Ernest Miguelez, S. Usai, F. Wishlade   +13 more
semanticscholar   +1 more source

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source

Rebuilding the broken walls of Zimbabwe with the Church, leadership and followership

Verbum et Ecclesia
Biblically and historically, Christianity is meant to enlighten people, transform lives, and develop responsible and effective leaders and followers who influence life-building change across generations and borders.
Kimion Tagwirei
doaj   +1 more source

The Bible as seedbed for revival in the 21st century

In die Skriflig, 2020
One of the key slogans of the Reformation is ecclesia reformata semper reformanda [a reformed church should always be reforming]. The constant reformation and renewal of the church always was, and still is, a key factor in the longevity of the church in ...
Johannes M. Wessels
doaj   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

Special Relativistic Simulations of Magnetically-dominated Jets in Collapsing Massive Stars

, 2008
We perform a series of two-dimensional magnetohydrodynamic core-collapse simulations of rapidly rotating and strongly magnetized massive stars. To study the properties of magnetic explosions for a longer time stretch of postbounce evolution, we develop a
Akiyama, Aloy, Anninos, Asano, Asano, Barkov, Bucciantini, Burrows, De Villiers, De Villiers, Fujimoto, Ghisellini, Harding, Hawley, Heger, Heger, Ibrahim, Israel, Katsuhiko Sato, Kei Kotake, Koide, Komissarov, Kotake, Kotake, Kotake, Krolik, MacFadyen, Maeda, Maeda, Masada, Matt, Meszaros, Metzger, Mizuno, Mizuno, Mizuta, Nagataki, Nishikawa, Nishimura, Paczynski, Piro, Proga, Qian, Rea, Rea, Salmonson, Savaglio, Sawai, Sawai, Shapiro, Stanek, Stanek, Stone, Suwa, Suwa, Takahashi, Takiwaki, Thompson, Thompson, Thompson, Toma, Tomoya Takiwaki, Uzdensky, Uzdensky, Wheeler, Woosley, Yamada, Zhang, Zhang   +68 more
core   +1 more source

Connexin 26 Functions as a Direct Transcriptional Regulator During the Cochlea Development

Advanced Science, EarlyView.
Connexin26 can not only form intercellular channels that mediate rapid communication on the cell membrane, but also enter the nucleus as a transcription factor to directly regulate the transcription of nuclear genes. In the developing cochlea, Cx26 can control the maturation of the molecular scissor ADAM10 by regulating the transcription of TspanC8 ...
Xiaozhou Liu, Le Xie, Yuan Jin, Sen Chen, Xinyu Shi, Yanjun Zong, Zhengdong Zhao, Wei‐Jia Kong, Yu Sun   +8 more
wiley   +1 more source

Immigration and the U.S. Labor Market: Public Policy Gone Awry [PDF]

, 1992
[Excerpt] One of the least discussed, yet most significant influences upon contemporary economic affairs in the United States, has been the post-1965 revival of mass ...
Briggs, Vernon M., Jr.
core   +1 more source