Results 81 to 90 of about 119,685 (321)

Room‐Temperature Helix‐to‐Disc Conversion of Thia[6]helicene S,S‐Dioxides to Coronene via In Situ Phenoxide Anion Generation

open access: yesChemistry – A European Journal, EarlyView.
In situ phenoxide formation at the benzene terminus triggers room‐temperature conversion of thia[6]helicene S,S‐dioxides to coronene. The solubility contrast drives product precipitation, enabling isolation by simple filtration. This pericyclic annulation between the helical termini provides direct access to coronene‐type planar architectures ...
Kaito Seino, Takashi Murase
wiley   +1 more source

More Than a Question of Correlation: Characterization of the Evidentiary Basis for Biomarker Surrogates Used in European Marketing Authorizations

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Traditionally, clinical outcomes measuring how a patient feels, functions, or survives are preferred endpoints in clinical trials; however, some may take a long time to manifest in slowly developing diseases. Biomarkers, if properly validated, can serve as surrogate endpoints, acting as substitutes for clinical outcomes.
Renske Johanna Grupstra   +4 more
wiley   +1 more source

A Survey on Credential Revocation and DID Deactivation in Self-Sovereign Identity Systems

open access: yesIEEE Access
Self-Sovereign Identity (SSI) enables user-controlled identity management based on Decentralized Identifiers (DIDs) and Verifiable Credentials (VCs).
Younho Lee, Hojune Shin, Daeseon Choi
doaj   +1 more source

Security Analysis of Vehicular Ad Hoc Networks (VANET)

open access: yes, 2012
Vehicular Ad Hoc Networks (VANET) has mostly gained the attention of today's research efforts, while current solutions to achieve secure VANET, to protect the network from adversary and attacks still not enough, trying to reach a satisfactory level, for ...
Samara, Ghassan
core   +1 more source

Sudan at War With Itself: Civilian Devastation in the Civil War

open access: yesConflict Resolution Quarterly, EarlyView.
ABSTRACT A civil war is raging in Sudan between the Sudan Armed Forces (SAF) and the Rapid Support Forces (RSF) along with militia groups. Beginning on April 15, 2023, and continuing at least to this writing (October 15, 2025), civilian noncombatants have been subjected to bombings, beatings, torture, shootings, rape, and murder on a large scale. Since
Daniel Rothbart   +3 more
wiley   +1 more source

Recent Developments in the Field of Air‐Stable Nickel(0) Precatalysts for Cross‐Coupling Reactions

open access: yesEuropean Journal of Inorganic Chemistry, EarlyView.
The development of bench‐stable Ni(0) sources aims to replace air‐sensitive [Ni(COD)2] (cod = cycloocta‐1,5‐diene) with easy‐to‐handle alternatives. Through a targeted ligand design, using electron‐deficient dienes, carbenes, and fluorophosphines, researchers have achieved air‐ and moisture‐tolerant complexes that show high catalytic activity in cross ...
Franziska Flecken, Schirin Hanf
wiley   +1 more source

Synthesis of Sulfur Heterocycles by Palladium‐Catalyzed Cyclization

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
In spite of the well‐known palladium thiophilicity, sulfur‐containing acyclic substrates may efficiently undergo several different kinds of palladium‐catalyzed cyclization processes leading to highly important sulfur heterocycles in one synthetic step. Advances in this challenging and stimulating field of research are presented in this review.
Bartolo Gabriele
wiley   +1 more source

Spontaneous regression of equine sarcoids is an exceptional event

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Sarcoids are benign, yet locally aggressive skin tumours that commonly affect horses and other equid species. The lesions are induced by bovine papillomavirus types 1, 2, and probably 13 in conjunction with other factors including trauma and a genetic predisposition.
Sabine Brandt
wiley   +1 more source

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