Results 61 to 70 of about 2,598,195 (380)
The Scientific Revolution of Thomas Kuhn and Their Relevances for Humanization of Islamic Law [PDF]
, 2016 This paper tries to explore the views of Thomas Kuhn that science is moving through the stages that will culminate in normal conditions and then "rot" because it has been replaced by science or new paradigm. So next.
Kamal, M. A. (Muhamad)
core
Gaseous Detector with Sub-keV Threshold to Study Neutrino Scattering at Low Recoil Energies
Advances in High Energy Physics, 2014 Gaseous detector with a sub-keV electron equivalent threshold is a very perspective tool for the precision measurement of the neutrino magnetic moment and for observing coherent scattering of neutrinos on nuclei.
A. V. Kopylov +3 more
doaj +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Green revolution 2.0: a sustainable energy path [PDF]
, 2010 This repository item contains a single issue of Sustainable Development Insights, a series of short policy essays that began publishing in 2008 by the Boston University Frederick S. Pardee Center for the Study of the Longer-Range Future. The series seeks
Kulatilaka, Nalin
core +1 more source
Transforming Africa’s food systems: a smallholder farmers’ perspective
Global Social Challenges Journal, 2023 The 2021 UN Food Systems Summit (UNFSS) awakened the world to the critical need for food systems transformation. Several commitments were made during the summit, with the UN Secretary-General reiterating the need to support national mechanisms that ...
Mutyasira Vine
doaj +1 more source
Liquid for Fused Deposition Modeling Technique (L-FDM)—A Revolution in Application Chemicals to 3D Printing Technology: Color and Elements [PDF]
, 2023 Robert E. Przekop +3 more
openalex +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
On the existence of infinitely many closed geodesics on orbifolds of revolution [PDF]
, 2006 Using the theory of geodesics on surfaces of revolution, we introduce the period function. We use this as our main tool in showing that any two-dimensional orbifold of revolution homeomorphic to S^2 must contain an infinite number of geometrically ...
Borzellino, Joseph E. +3 more
core +3 more sources
TREX1, a predator for treating MSI‐H tumors?
Molecular Oncology, EarlyView.Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya +2 more
wiley +1 more source