Results 61 to 70 of about 2,053,687 (333)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
On the existence of infinitely many closed geodesics on orbifolds of revolution [PDF]
, 2006 Using the theory of geodesics on surfaces of revolution, we introduce the period function. We use this as our main tool in showing that any two-dimensional orbifold of revolution homeomorphic to S^2 must contain an infinite number of geometrically ...
Borzellino, Joseph E. +3 more
core +3 more sources
Synthesis, characterization and investigation of biodistribution of dendrimer-amiloride nanoconjugate using single photon computed tomography technique in animal sample [PDF]
Nanomedicine JournalObjective(s): Amiloride is a pyrazine compound that inhibits the reabsorption of sodium by blocking sodium channels in the cells of the renal cortex. It has demonstrated promising efficacy in the treatment of cancer in recent times.
Sheida Iranpour +5 more
doaj +1 more source
Transforming Africa’s food systems: a smallholder farmers’ perspective
Global Social Challenges Journal, 2023 The 2021 UN Food Systems Summit (UNFSS) awakened the world to the critical need for food systems transformation. Several commitments were made during the summit, with the UN Secretary-General reiterating the need to support national mechanisms that ...
Mutyasira Vine
doaj +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
France\u27s Financial Crisis: Analyzing the Role of the Finance Minister [PDF]
, 2015 The downfall of France\u27s Old Regime and the beginning of the French Revolution were largely caused by the financial crisis plaguing France. Since the Seven Year\u27s War, France\u27s finances had suffered and were spiraling out of control.
Smith, Jadon B
core +1 more source
Molecular Oncology, EarlyView.RAS‐targeted therapies have become a clinical reality. Although promising results in patients have been achieved, there are still challenges ahead such as coping with drug resistance. Here we summarize selected RAS inhibitors targeting either individual KRAS mutant isoforms (KRASG12C, KRASG12D, KRASG12V) or exhibiting a wider inhibitory spectrum ...
Matthias Drosten, Mariano Barbacid
wiley +1 more source
China's Organic Revolution [PDF]
, 2007 Agriculture in China is at the onset of an Organic Revolution. From 2000 to 2006, China has moved from 45th to 2nd position in the world in number of hectares under organic management.
Paull, John
core
Contributions to Four-Position Theory with Relative Rotations [PDF]
, 2009 We consider the geometry of four spatial displacements, arranged in cyclic order, such that the relative motion between neighbouring displacements is a pure rotation.
Schröcker, Hans-Peter
core +1 more source
Supporting Individuals and Families Impacted by Dementia in Counseling: Case Report
Journal of Patient Experience, 2022 As more than 6 million people in the United States are living with dementia, it is important to foster and train counselors who are specialized in dementia.
Kathy Lee PhD, LMSW +2 more
doaj +1 more source