Results 61 to 70 of about 1,962,936 (310)

Contributions to Four-Position Theory with Relative Rotations [PDF]

, 2009
We consider the geometry of four spatial displacements, arranged in cyclic order, such that the relative motion between neighbouring displacements is a pure rotation.
Schröcker, Hans-Peter
core   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Banal revolution: the emptying of a political signifier [PDF]

, 2013
If you type in the word ‘revolution’ in the Google search engine the top result that comes up is a chain of bars called Revolution. Other results on the first page of the search engine include a commercial radio station, clothing, a skate park and a ...
Cammaerts, Bart
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Gaseous Detector with Sub-keV Threshold to Study Neutrino Scattering at Low Recoil Energies

Advances in High Energy Physics, 2014
Gaseous detector with a sub-keV electron equivalent threshold is a very perspective tool for the precision measurement of the neutrino magnetic moment and for observing coherent scattering of neutrinos on nuclei.
A. V. Kopylov, I. V. Orekhov, V. V. Petukhov, A. E. Solomatin   +3 more
doaj   +1 more source

Peer-to-Peer and Mass Communication Effect on Revolution Dynamics

, 2012
Revolution dynamics is studied through a minimal Ising model with three main influences (fields): personal conservatism (power-law distributed), inter-personal and group pressure, and a global field incorporating peer-to-peer and mass communications ...
A. Kindler, Adler, Aizenman, Bornholdt, Bouchaud, Bouchaud, Callen, Cantono, Cantono, D. Stauffer, Dalle, de Oliveira, Goldenberg, Gonçalves, Gordon, Granovetter, Holroyd, Le Breton, Milgram, Milgram, Nadal, Phan, S. Solomon, Schelling, Solomon, Soros, Stauffer, Stauffer, Steger, Tomochi   +29 more
core   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

On the existence of infinitely many closed geodesics on orbifolds of revolution [PDF]

, 2006
Using the theory of geodesics on surfaces of revolution, we introduce the period function. We use this as our main tool in showing that any two-dimensional orbifold of revolution homeomorphic to S^2 must contain an infinite number of geometrically ...
Borzellino, Joseph E., Jordan-Squire, Christopher R., Petrics, Gregory C., Sullivan, D. Mark   +3 more
core   +3 more sources