Decreased reward circuit connectivity during reward anticipation in major depression [PDF]
NeuroImage: Clinical, 2022 An important symptom of major depressive disorder (MDD) is the inability to experience pleasure, possibly due to a dysfunction of the reward system.
Hanneke Geugies +7 more
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Neural bases of reward anticipation in healthy individuals with low, mid, and high levels of schizotypy [PDF]
Scientific Reports, 2023 A growing body of research has placed the ventral striatum at the center of a network of cerebral regions involved in anticipating rewards in healthy controls.
F. Carruzzo +5 more
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Altered brain activation during reward anticipation in bipolar disorder [PDF]
Translational Psychiatry, 2022 Although altered reward sensitivity has been observed in individuals with bipolar disorder (BD), the brain function findings related to reward processing remain unexplored and inconsistent.
Xipeng Long +5 more
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Increased ventral striatal functional connectivity in patients with schizophrenia during reward anticipation [PDF]
NeuroImage: Clinical, 2022 Background: Growing evidence points towards dysfunction of the ventral striatum as a neural substrate of motivational impairments in schizophrenia. Ventral striatal activity during reward anticipation is generally reduced in patients with schizophrenia ...
Fabien Carruzzo +4 more
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Exploratory study of associations between monetary reward anticipation brain responses and mu-opioid signalling in alcohol dependence, gambling disorder and healthy controls [PDF]
NeuroImage: ReportsAlcohol dependence (AD) and gambling disorder (GD) are common addiction disorders with significant physical and mental health consequences. AD and GD are associated with dysregulated responses to reward which could be due to a common mechanism of ...
Samuel Turton +9 more
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Neural substrates of reward anticipation and outcome in schizophrenia: a meta-analysis of fMRI findings in the monetary incentive delay task [PDF]
Translational Psychiatry, 2022 Dysfunction of the mesocorticolimbic dopaminergic reward system is a core feature of schizophrenia (SZ), yet its precise contributions to different stages of reward processing and their relevance to disease symptomology are not fully understood.
Jianguang Zeng +6 more
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Chronic stress deficits in reward behaviour co-occur with low nucleus accumbens dopamine activity during reward anticipation specifically [PDF]
Communications BiologyWhilst reward pathologies are major and common in stress-related neuropsychiatric disorders, their neurobiology and treatment are poorly understood. Imaging studies in human reward pathology indicate attenuated BOLD activity in nucleus accumbens (NAc ...
Chenfeng Zhang +8 more
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Atypical reward anticipation in impulsive individuals: evidence from EEG and experiential delay discounting [PDF]
Frontiers in PsychologyBackgroundImpulsivity is characterized by impaired inhibition of thoughts and actions and a reduced ability to weigh the consequences of behavior.
Felix Zakirov, Olga Sysoeva
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Altered neural signalling during reward anticipation in children and early adolescents with high psychotic-like experiences [PDF]
NeuroImage: ClinicalBackground: Schizophrenia is associated with abnormalities in neurodevelopmental processes. Furthermore, dysfunctional neural circuits involved in reward processing may be linked to the development of symptoms in schizophrenia and are predictive of long ...
Pritha Sen, Franziska Knolle
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Assessing hypo-arousal during reward anticipation with pupillometry in patients with major depressive disorder: replication and correlations with anhedonia [PDF]
Scientific ReportsMajor depressive disorder (MDD) is a devastating and heterogenous disorder for which there are no approved biomarkers in clinical practice. We recently identified anticipatory hypo-arousal indexed by pupil responses as a candidate mechanism subserving ...
Andy Brendler +11 more
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