Results 71 to 80 of about 42,035 (259)

Resilience relationship with effort-reward imbalance mediated by teaching emotions in elementary teachers of Taft City [PDF]

طب کار
Introduction:  The imbalance between reward and effort, characterized by the disparity between effort put in and rewards received, can be greatly affected by personal abilities and feelings.
Fatemeh Jannesar, Ahmad Zandvanian Naeini, Hossain Hassani   +2 more
doaj  

Impact of energy price scheme and rewarding strategies on mobilizing the flexibility of residential end-users and aggregator’s profit

International Journal of Electrical Power & Energy Systems
In incentive-based demand response programs, the aggregator sends reward signals to the consumers to stimulate consumption changes for mobilizing their flexibility in energy end-uses, which can then be traded in different markets.
Vahid Rasouli, Álvaro Gomes, Carlos Henggeler Antunes   +2 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

The Impact of Leadership, Reward Systems, and Teacher Commitment on the Effectiveness of Islamic Senior High Schools: A Path Analysis Approach

Al-Tanzim: Jurnal Manajemen Pendidikan Islam
This study examines the influence of school Leadership, reward systems, and teacher commitment on the effectiveness of private Islamic Senior High Schools (Madrasah Aliyah) in one province in Indonesia.
Fahrina Yustiasari Liriwati, Zulhimma Zulhimma, Zulhammi Zulhammi, Armizi Armizi   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Green loyalty? Unveiling consumer preferences in sustainable temporary loyalty programs

Cleaner and Responsible Consumption
Almost every food retailer offers them – temporary loyalty programs (TLPs). TLPs aim to enhance customer loyalty by offering enticing, product-based incentives.
Caspar Krampe, Anne-Jeth de Groot, William Hurst   +2 more
doaj   +1 more source