An Economic Analysis of Property Rights in Information: Justifications and Problems of Exclusive Rights, Incentives to Generate Information, and the Alternative of a Government-Run Reward System [PDF]
, 1998 This article examines and questions the traditional justifications for intellectual property (I.P.) rights in America (focusing on copyright and patent law), and explores incentives necessary to induce the creation of these works of information.
Calandrillo, Steve P.
core +2 more sources
Pathophysiological changes of neurofunctional interaction between the dopaminergic reward system and the hippocampus in schizophrenia and bipolar disorder [PDF]
, 2018 Sarah Wolter
openalex +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source
Individual attitudes, organizational reward system and patenting performance of R&D scientists and engineers [PDF]
The interactive process perspective of innovation suggests that the innovation performance of individual R&D scientist or engineers (RSEs) is influenced by a nexus of interaction between individual attributes and organizational characteristics.
Lee, Lena, Wong, Poh Kam
core +1 more source
FEBS Open Bio, EarlyView.This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source
Music Listening as Kangaroo Mother Care: From Skin-to-Skin Contact to Being Touched by the Music
AcousticsThe metaphor of being touched by music is widespread and almost universal. The tactile experience, moreover, has received growing interest in recent years.
Mark Reybrouck
doaj +1 more source
The ‘problem of problem choice’: A model of sequential knowledge production within scientific communities cientific communities. [PDF]
In this paper we present an original model of sequential problem choice within scientific communities. Disciplinary knowledge is accumulated by solving problems emerging in a growing tree-like web of research areas.
Jean-Michel Dalle, Nicolas Carayol
core
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source