Results 41 to 50 of about 23,549,597 (312)

Modulation of anti-tumor immunity by the brain’s reward system

open access: yesNature Communications, 2018
Regulating immunity is a leading target for cancer therapy. Here, we show that the anti-tumor immune response can be modulated by the brain’s reward system, a key circuitry in emotional processes.
T. Ben-Shaanan   +10 more
semanticscholar   +1 more source

Altered reward system reactivity for personalized circumscribed interests in autism

open access: yesMolecular Autism, 2018
BackgroundNeurobiological research in autism spectrum disorders (ASD) has paid little attention on brain mechanisms that cause and maintain restricted and repetitive behaviors and interests (RRBIs).
G. Kohls   +4 more
semanticscholar   +1 more source

A homolog of the vertebrate pituitary adenylate cyclase-activating polypeptide is both necessary and instructive for the rapid formation of associative memory in an invertebrate [PDF]

open access: yes, 2010
Similar to other invertebrate and vertebrate animals, cAMP dependent signaling cascades are key components of long-term memory (LTM) formation in the snail Lymnaea stagnalis, an established experimental model for studying evolutionarily conserved ...
Kemenes, György   +5 more
core   +1 more source

Antecedents and consequences affecting job plateau among school employees in Tehran [PDF]

open access: yesمدیریت و چشم انداز آموزش
The purpose of the present study is to investigate the antecedents and consequences of job burnout among school employees in Tehran. According to its purpose, the research method is applicable, pragmatic in terms of paradigm, and qualitative in terms of ...
Nafiseh Ghasemi Zargar   +3 more
doaj   +1 more source

The Value-of-Information in Matching with Queues

open access: yes, 2015
We consider the problem of \emph{optimal matching with queues} in dynamic systems and investigate the value-of-information. In such systems, the operators match tasks and resources stored in queues, with the objective of maximizing the system utility of ...
Bishop C., Chung F.
core   +1 more source

Lack of Bmal1 leads to changes in rhythmicity and impairs motivation towards natural stimuli

open access: yesOpen Biology
Maintaining proper circadian rhythms is essential for coordinating biological functions in mammals. This study investigates the effects of daily arrhythmicity using Bmal1-knockout (KO) mice as a model, aiming to understand behavioural and motivational ...
Paula Berbegal-Sáez   +7 more
doaj   +1 more source

Speciation Through the Lens of Population Dynamics: A Theoretical Primer on How Small and Large Populations Diverge

open access: yesPopulation Ecology, EarlyView.
Population size and dynamics fundamentally shape speciation by influencing genetic drift, founder events, and adaptive potential. Small populations may speciate rapidly due to stronger drift, whereas large populations harbor more genetic diversity, which can alter divergence trajectories. We highlight theoretical models that incorporate population size
Ryo Yamaguchi   +3 more
wiley   +1 more source

An Examination of the Multi-Faceted Motivation System in Healthy Young Adults

open access: yesFrontiers in Psychiatry, 2018
Background: Amotivation is a prevalent symptom in schizophrenia (SZ) and depression (MDD), and is linked to poor functional outcomes in affected individuals.
Susana Da Silva   +19 more
doaj   +1 more source

On Tractarian law [PDF]

open access: yes, 1979
"'It is clear", wrote Wittgenstein in the Tractatus, "that ethics has nothing to do with punishment and reward in the usual sense of the terms" (6.422).
Smith, Barry
core  

Neuronal and psychological underpinnings of pathological gambling [PDF]

open access: yes, 2014
Like in the case of drugs, gambling hijacks reward circuits in a brain which is not prepared to receive such intense stimulation. Dopamine is normally released in response to reward and uncertainty in order to allow animals to stay alive in their ...
Anselme   +18 more
core   +3 more sources

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