Results 71 to 80 of about 1,011,379 (271)
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Molecular Oncology, EarlyView.A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He +8 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Antecedents and consequences affecting job plateau among school employees in Tehran [PDF]
مدیریت و چشم انداز آموزشThe purpose of the present study is to investigate the antecedents and consequences of job burnout among school employees in Tehran. According to its purpose, the research method is applicable, pragmatic in terms of paradigm, and qualitative in terms of ...
Nafiseh Ghasemi Zargar +3 more
doaj +1 more source
Rewards versus Intellectual Property Rights [PDF]
This paper compares reward systems to intellectual property rights (patents and copyrights). Under a reward system, innovators are paid for innovations directly by government (possibly on the basis of sales), and innovations pass immediately into the ...
Steven Shavell, Tanguy van Ypersele
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Is Rewarding Beneficial to Behavior? [PDF]
, 2013 What effect does a reward system have on ninth grade student behavior? Is there a way to have my students behave better than they currently are? There is plenty of research that has been conducted on different types of distracting behavior as well as ...
Webb, John
core +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Moving Forward with the BAS: Towards a Neurobiology of Multidimensional Model of Approach Motivation
Psychological Topics, 2017 One of the hottest topics in neuroscience is the study of brain-behavioural circuits underlying the processing of reward-related stimuli. A growing body of studies has shed new light on the neural structure of this reward system.
Dino Krupić, Philip J. Corr
doaj +2 more sources
The Maximum Traveling Salesman Problem with Submodular Rewards [PDF]
, 2012 In this paper, we look at the problem of finding the tour of maximum reward on an undirected graph where the reward is a submodular function, that has a curvature of $\kappa$, of the edges in the tour. This problem is known to be NP-hard.
Jawaid Stephen, L. Smith, Syed Talha
core