Rewarming Injury after Cold Preservation [PDF]
Organ dysfunction pertinent to tissue injury related to ischemic ex vivo preservation during transport from donor to recipient still represents a pivotal impediment in transplantation medicine. Cold storage under anoxic conditions minimizes metabolic activity, but eventually cannot prevent energetic depletion and impairment of cellular signal ...
Thomas Minor, Charlotte von Horn
openaire +6 more sources
Background Accidental hypothermia (AH) is defined as an involuntary decrease in core body temperature to
Makoto Watanabe +14 more
doaj +2 more sources
Experiments and simulations demonstrating the rapid ultrasonic rewarming of frozen tissue cryovials. [PDF]
The development of methods to safely rewarm large cryopreserved biological samples remains a barrier to the widespread adoption of cryopreservation. Here, experiments and simulations were performed to demonstrate that ultrasound can increase rewarming ...
Rui Xu, B. Treeby, E. Martin
semanticscholar +1 more source
Reduction of Afterdrop by Using Active External Warming During Treatment of Accidental Hypothermia-A Randomized, Crossover Trial. [PDF]
ABSTRACT Introduction This study investigates the impact of active external warming on afterdrop in simulated accidental hypothermia, compared to the effect of passive warming measures. Methods This study used data from a randomized crossover field study of experimental hypothermia.
Mydske S +8 more
europepmc +2 more sources
Rapid vs. Slow Rewarming for Management of Moderate to Severe Hypothermia in Low-Birth-Weight Pre-term Neonates—An Open Label Randomized Controlled Trial [PDF]
BACKGROUND Evidence is lacking regarding the optimal method of rewarming hypothermic low-birth-weight (LBW) pre-term neonates. We aim to evaluate the effect of rapid vs.
Prerana Jain +2 more
openalex +2 more sources
Cold-Induced Suppression of Myogenesis in Skeletal Muscle Stem Cells Contributes to Delayed Muscle Regeneration During Hibernation. [PDF]
Hibernating mammals preserve satellite cell viability during extreme cold exposure by suppressing ferroptosis through elevated GPX4 expression. Although these cells survive cold stress, myogenic activation and differentiation are markedly reduced, leading to delayed muscle regeneration in vivo.
Miyaji T +12 more
europepmc +2 more sources
Abrupt return to normothermia has been shown a genuine factor contributing to graft dysfunction after transplantation. This study tested the concept to mitigate reperfusion injury of liver grafts by gentle warming‐up using ex vivo machine perfusion prior
T. Minor +8 more
semanticscholar +1 more source
Background. Normothermic machine perfusion (NMP) is typically performed after a period of hypothermic preservation, which exposes the kidney to an abrupt increase in temperature and intravascular pressure.
B. Ogurlu +7 more
semanticscholar +1 more source
Vitrification and Rewarming of Magnetic Nanoparticle-Loaded Rat Hearts
To extend the preservation of donor hearts beyond the current 4–6 h, this paper explores heart cryopreservation by vitrification—cryogenic storage in a glass‐like state. While organ vitrification is made possible by using cryoprotective agents (CPA) that
Zhe Gao +16 more
semanticscholar +1 more source
Relation between finger cold-induced vasodilation and rewarming speed after cold exposure [PDF]
PurposeThe risk for local cold injuries has been linked to poor cold-induced vasodilation (CIVD) during cold exposure and to poor rewarming after cold exposure.
C. F. Kingma +2 more
openalex +2 more sources

