Results 101 to 110 of about 321,292 (267)

Le travail du commun : retours de Mrs Dalloway dans Les Veilleurs de chagrin de Nicole Roland

open access: yesÉtudes Britanniques Contemporaines, 2015
Virginia Woolf’s Mrs Dalloway is the major intertext of Les Veilleurs de chagrin, Nicole Roland’s novel. Not only is Mrs Dalloway omnipresent by the numerous quotations and allusions to it, but a copy of the book circulates with the protagonist ...
Anne-Laure Rigeade
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

De la biographie criminelle à l’autobiographie spirituelle : emprunts, réécriture et autoréécriture chez Defoe

open access: yesXVII-XVIII, 2019
Roxana (1724) is Daniel Defoe’s last “criminal novel” – or at least it is designated as such nowadays by some critics. The issue of literary genre is problematic when we talk about the criminal narratives written by Defoe in the 1720s since he wrote both
Emmanuelle Peraldo
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

The Language in the Common-Sense Speech: ideology and imaginary

open access: yesSignum: Estudos da Linguagem, 2019
This research is part of our Master’s thesis, and it proposes to analyze the statements expressed in the common sense about the language, in order to understand which ideology and the linguistic imaginary that cross these statements.
Rejane Beatriz Fiepke Carpenedo   +1 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Computation in chemical graph rewriting networks

open access: yesJournal of Physics: Complexity
Biological systems are frequently viewed as performing computations that are implemented by chemical transformations underlying the turn-over of their molecular components.
Christoph Flamm   +2 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy