Results 101 to 110 of about 324,410 (283)
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Joan Maragall: creació, traducció i reescriptura
What is the role of translation in Maragall’s work? If his first goal was to bestow cultural support to Catalan literature with the addition of the European authors of Modernism, the second stage of the Catalan poet’s agenda becomes more ambitious ...
Francesco Ardolino
doaj
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Computing Horn Rewritings of Description Logics Ontologies
We study the problem of rewriting an ontology O1 expressed in a DL L1 into an ontology O2 in a Horn DL L2 such that O1 and O2 are equisatisfiable when extended with an arbitrary dataset.
Grau, Bernardo Cuenca, Kaminski, Mark
core
Development of human monoclonal antibodies against TARM1 by yeast display
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
Computation in chemical graph rewriting networks
Biological systems are frequently viewed as performing computations that are implemented by chemical transformations underlying the turn-over of their molecular components.
Christoph Flamm +2 more
doaj +1 more source
This article first sketches out the legacy of The Woman in White and the sensation novel of the 1860s from the late-Victorian period to the present day.
Catherine Delyfer
doaj +1 more source
Re-Working Shakespeare: Heiner Müller’s Macbeth
This article focuses on particular meanings of the term “work,” as related first to the process of adapting Shakespeare and secondly to the ideological and philosophical resonances of this term as employed in the socialist propaganda in East Germany and ...
Nicolaescu Mădălina
doaj +1 more source

