Results 51 to 60 of about 31,656 (296)
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
FEBS Letters, EarlyView.The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke +2 more
wiley +1 more source
A significação conceitual pela escrita e reescrita orientada em aulas de Química
Química Nova, 2014 In this paper, the practice of guided writing and rewriting in Chemistry classes on a graduate degree in Science is shown as a teaching method that promotes conceptual meaning in Chemistry among students.
Judite Scherer Wenzel +1 more
doaj +1 more source
Corela, 2020 As a thinker of a fragmented thruth, the apologist of the Pensées co-enunciates as an "honnête homme" what he over-enunciates as a Christian. The enunciature "posture" therefore casts a new light on the dialectical movement at work in Pascal's logic and
Laurent Susini
doaj +1 more source
A working model for cytoplasmic assembly of H/ACA snoRNPs
FEBS Letters, EarlyView.Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
Heterogenesis in Musical Rewriting and (Re)Performance
Musica Theorica, 2019 In the music of the Twentieth Century, Luciano Berio perhaps is one of the most concerned composers with musical rewriting, intercrossing several traditions, from either European music or traditional cultures.
Silvio Ferraz Mello Filho +1 more
doaj +1 more source
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
FEBS Letters, EarlyView.Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
FEBS Letters, EarlyView.Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Die spore van Raka: Oor herskrywing en kanonisering (Deel 2)
Tydskrif vir Letterkunde, 2017 Every literary system possesses a canon with the classical canon as the most stable and simultaneously the one with the most restrictive access. Writers and texts can only maintain their position within the canon through continuous rewriting: critical ...
H.P. Van Coller, A. Van Jaarsveld
doaj
Effondrement ou ensevelissement : les modalités d’une logique conservatrice dans The Mists of Avalon
Caliban: French Journal of English Studies, 2020 This paper aims at exploring the dynamics of erosion and collapse that can be observed throughout a neo-pagan rewriting of the Matter of Britain, The Mists of Avalon by Marion Zimmer Bradley (1982), that played a significant part in the popularization of
Manon Berthier
doaj +1 more source