Results 71 to 80 of about 333,009 (323)

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Complexity Hierarchies and Higher-order Cons-free Term Rewriting [PDF]

open access: yes, 2017
Constructor rewriting systems are said to be cons-free if, roughly, constructor terms in the right-hand sides of rules are subterms of the left-hand sides; the computational intuition is that rules cannot build new data structures.
Kop, Cynthia, Simonsen, Jakob Grue
core   +2 more sources

Die spore van Raka: Oor herskrywing en kanonisering (Deel 2)

open access: yesTydskrif vir Letterkunde, 2017
Every literary system possesses a canon with the classical canon as the most stable and simultaneously the one with the most restrictive access. Writers and texts can only maintain their position within the canon through continuous rewriting: critical ...
H.P. Van Coller, A. Van Jaarsveld
doaj  

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

Die spore van Raka: oor herskrywing en kanonisering (Deel 1)

open access: yesTydskrif vir Letterkunde, 2017
Every literary system possesses a canon with the classical canon as the most stable and simultaneously the one with the most restrictive access. Writers and texts can only maintain their position within the canon through continuous rewriting: critical ...
H. P. Van Coller, A. Van Jaarsveld
doaj  

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Encapsulation for Practical Simplification Procedures [PDF]

open access: yes, 2003
ACL2 was used to prove properties of two simplification procedures. The procedures differ in complexity but solve the same programming problem that arises in the context of a resolution/paramodulation theorem proving system. Term rewriting is at the core
Matlin, Olga Shumsky, McCune, William
core   +2 more sources

Fabriquer un escalier : « La Scala d’Oro », une collection pour l’enfance en Italie dans les années 30

open access: yesStrenae, 2016
"La Scala d'Oro" is one of the most famous Italian Children’s Book collections. Created by two intellectuals, Fernando Palazzi and Vincenzo Errante, who were responsible for the choice of texts and authors, it was published in Turin by UTET between 1932 ...
Elisa Rebellato
doaj   +1 more source

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