Results 71 to 80 of about 31,656 (296)
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Journal of Algebra, 2011 AbstractA group G is said to have the n-rewritable property Qn if for all elements g1,g2,…,gn∈G, there exist two distinct permutations σ,τ∈Symn such that gσ(1)gσ(2)⋯gσ(n)=gτ(1)gτ(2)⋯gτ(n). We show here that if G satisfies Qn, then G has a characteristic subgroup N such that |G:N| and |N′| are both finite and have sizes bounded by functions of n.
Elashiry, M.I., Passman, D.S.
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Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Theoretical Computer Science, 1987 \textit{J. C. Raoult} [ibid. 32, 1-24 (1984; Zbl 0551.68065)] has given a description of graph rewriting. His description is operational, despite the similarity which his constructions have to the category-theoretic concept of a pushout. We describe a modification to Raoult's description of graph rewriting which allows the reduction of a redex to be ...
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, 2021 We present a way to implement term rewriting on a GPU. We do this by letting the GPU repeatedly perform a massively parallel evaluation of all subterms. We find that if the term rewrite systems exhibit sufficient internal parallelism, GPU rewriting substantially outperforms the CPU.
Johri van Eerd +4 more
openaire +6 more sources
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Strenae, 2016 "La Scala d'Oro" is one of the most famous Italian Children’s Book collections. Created by two intellectuals, Fernando Palazzi and Vincenzo Errante, who were responsible for the choice of texts and authors, it was published in Turin by UTET between 1932 ...
Elisa Rebellato
doaj +1 more source
Electronic Notes in Theoretical Computer Science, 2007 In this paper, we present a term rewriting based library for manipulating Java bytecode. We define a mapping from bytecode programs to algebraic terms, and we use Tom, an extension of Java that adds pattern-matching facilities, to describe transformations. An originality of Tom is that it provides a powerful strategy language to express traversals over
Balland, Emilie +2 more
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Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source