Results 151 to 160 of about 231,693 (293)

Radial outer retina reflectivity (RORR) sign in LAMP2‐associated retinopathy

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To describe the radial outer retina reflectivity (RORR) sign in patients carrying pathogenic variants in the X‐linked lysosome‐associated membrane protein‐2 (LAMP2) gene and to review the histologic characteristics of LAMP2 expression in the human retina.
Rachael C. Heath Jeffery   +17 more
wiley   +1 more source

Role of salt levels in rabbit skin preservation on the physical properties, structural, thermal and molecular stability of rabbit fur leather

open access: yesWorld Rabbit Science
Rabbit skin is particularly vulnerable to rapid degradation due to microbial attack during preservation prior to tanning. Therefore, proper preservation essential to maintain its quality.
Raden Lukas Martindro Satrio Ari Wibowo   +5 more
doaj   +1 more source

Rifaximin ameliorates memory impairment and Alzheimer's pathological changes in APP/PS1 mice associated with changes in the gut microbiome–bile acids–serum metabolites networks

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Modifying the brain–gut–microbiota axis has emerged as a promising therapeutic strategy against Alzheimer's disease (AD). Whether rifaximin, a non‐absorbed and non‐systemic antibiotic, can be applied to the treatment of AD remains unexplored.
Di Wu   +7 more
wiley   +1 more source

Genetic diversity of eighth exon of lamb3 in white Rex Rabbit.

open access: yes, 2016
Genetic diversity of eighth exon of lamb3 in white Rex Rabbit.
Xinsheng Wu (2213563)   +6 more
core   +1 more source

The c‐Src inhibitor eCF506 diminishes opioid tolerance and reduces β‐arrestin2 recruitment

open access: yesBritish Journal of Pharmacology, EarlyView.
Morphine activation of μ receptors causes tolerance through c‐Src activation and β‐arrestin2 recruitment. c‐Src inhibition or degradation reduces β‐arrestin2 recruitment, μ receptor endocytosis, while causing receptor upregulation, all likely contributing to reduced morphine tolerance.
Samuel Singleton   +6 more
wiley   +1 more source

Effects of lifelong sulforaphane intake on behavioural, neurochemical and biomolecular dysfunctions in the BTBR T+ Itpr3tf/J mouse model of autism spectrum disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Created in BioRender. Schiavone, S. (2026). https://BioRender.com/cy0xq6z. Abstract Background and Purpose Autism spectrum disorders (ASD) are multifactorial neurodevelopmental conditions associated with oxidative stress and neuroinflammation across critical developmental periods.
Vladyslav Sikora   +8 more
wiley   +1 more source

Investigation of the mechanisms and modulation of irinotecan‐induced emesis in Suncus murinus

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Irinotecan is a widely used chemotherapeutic agent that frequently causes nausea and emesis. Its emetic mechanism of action is poorly understood and the choice of drugs to reduce nausea and emesis is largely empirical. Experimental Approach Using Suncus murinus, we examined (i) the dose–response and temporal profile of ...
Zengbing Lu   +7 more
wiley   +1 more source

Elevated IL‐4 and IL‐13 Expression in Hailey‐Hailey Disease: Evidence for Th2‐Mediated Pathogenesis and Targeted Treatment

open access: yesJournal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Hailey‐Hailey disease (HHD) is a rare autosomal dominant blistering disorder caused by mutations in the ATP2C1 gene, which impair keratinocyte adhesion through disrupted calcium signaling. While traditionally considered a structural defect, recent studies suggest that Th2‐mediated inflammation may exacerbate disease pathology ...
Simonetta I. Gaumond   +6 more
wiley   +1 more source

Large Igneous Province Record Through Time and Implications for Secular Environmental Changes and Geological Time‐Scale Boundaries

open access: yesGeophysical Monograph Series, Page 1-26., 2021

Exploring the links between Large Igneous Provinces and dramatic environmental impact

An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
Richard E. Ernst   +8 more
wiley  

+1 more source

Similar or Different? Configurations of Authenticity Across Museum Types

open access: yesCurator: The Museum Journal, EarlyView.
ABSTRACT Authenticity is traditionally regarded as playing a crucial role in museums, science centers, and memorials. However, despite this fact, authenticity has very different meanings in different (institutional) settings. This complicates shared communications across museum practices.
S. Schwan   +18 more
wiley   +1 more source

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