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A Reemergence of Reye's Syndrome
Archives of Pediatrics & Adolescent Medicine, 1994Reye's syndrome is a disorder of unknown cause. It is characterized by acute encephalopathy and fatty degeneration of the viscera, usually following a viral illness, particularly varicella or influenza. It has been associated with the use of aspirin during such infections.
W B, Poss, D D, Vernon, J M, Dean
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Archives of Pediatrics & Adolescent Medicine, 1982
Reye's syndrome is a condition affecting children that is manifested by cerebral edema and fatty infiltration of the viscera without evidence of an inflammatory response in these organs. Mortality in recent series has ranged from 23% to 41%, but the annual risk of this syndrome developing is only four to seven per 1 million for children younger than 18
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Reye's syndrome is a condition affecting children that is manifested by cerebral edema and fatty infiltration of the viscera without evidence of an inflammatory response in these organs. Mortality in recent series has ranged from 23% to 41%, but the annual risk of this syndrome developing is only four to seven per 1 million for children younger than 18
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The Indian Journal of Pediatrics, 1981
Ten cases of Reye syndrome are reported. Significant hypoglycemia was present in six cases, with hypoglycorrhachia in four. There was significant elevation of serum transaminases in nine cases. Histological examination of the liver revealed fatty degeneration in all of the cases biopsied. The prognosis was poor; nine children expired within 72 hours of
R H, Merchant +4 more
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Ten cases of Reye syndrome are reported. Significant hypoglycemia was present in six cases, with hypoglycorrhachia in four. There was significant elevation of serum transaminases in nine cases. Histological examination of the liver revealed fatty degeneration in all of the cases biopsied. The prognosis was poor; nine children expired within 72 hours of
R H, Merchant +4 more
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The Biochemistry of Reye's Syndrome
CRC Critical Reviews in Clinical Laboratory Sciences, 1982AbstractAnd I Daniel fainted, and was sick certain days; afterward I rose up, and did the king's business; and I was astonished at the vision, but none understood it.The Bible Daniel 8:27On the basis of the findings presented in this biochemical overview, it can be said that Reye's syndrome affects every major category of human metabolism.
Robert E. Brown +2 more
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Salicylate and Reye's Syndrome
Pediatrics, 1981Starko et at1 have written an interesting paper, their observations concerning the interaction of fever, viral illness, and salicylates in the pathogenesis of Reye's syndrome appear plausible. However, their data do not unequivocally support their conclusion "salicylate causes Reye's syndrome." Although the authors are investigating the ...
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Clinical Neuropharmacology, 1987
Reye syndrome, a reversible metabolic encephalopathy and hepatopathy, offers a unique opportunity to investigate the pharmacologic mechanisms by which a toxic-metabolic insult to mitochondria is translated into neurochemical and neurologic dysfunction. Similarity of some clinical and metabolic abnormalities between certain inborn errors of organic acid,
M R, Pranzatelli, D C, De Vivo
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Reye syndrome, a reversible metabolic encephalopathy and hepatopathy, offers a unique opportunity to investigate the pharmacologic mechanisms by which a toxic-metabolic insult to mitochondria is translated into neurochemical and neurologic dysfunction. Similarity of some clinical and metabolic abnormalities between certain inborn errors of organic acid,
M R, Pranzatelli, D C, De Vivo
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The Journal of Pediatrics, 1970
Acute encephalopathy with visceral fatty infiltration (Reye's syndrome) in twins, one of whom survived, afforded the opportunity to study the condition in vivo. Electron microscopic findings suggested that a reversible hepatic lesion was insolved in the pathogenesis; infection with herpes simplex may have been the immediate cause of the disease.
M M, Thaler +3 more
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Acute encephalopathy with visceral fatty infiltration (Reye's syndrome) in twins, one of whom survived, afforded the opportunity to study the condition in vivo. Electron microscopic findings suggested that a reversible hepatic lesion was insolved in the pathogenesis; infection with herpes simplex may have been the immediate cause of the disease.
M M, Thaler +3 more
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Salicylates and Reye's Syndrome
Pediatrics, 1981The recent article by Starko et al1 on aspirin in Reye's syndrome prompted us to review this issue in 43 consecutive patients seen at the University of Chicago since January 1975. Salicylate levels or toxicology screens that included measurement of salicylates were performed at the time of hospital admission in 37 of the 43 patients.
J H, Tonsgard, P R, Huttenlocher
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Salicylates and Reye's Syndrome
JAMA: The Journal of the American Medical Association, 1983To the Editor.— Daniels et al (1983; 249:1311), in their discussion of salicylate use and Reye's syndrome, seem to use the terms aspirin and salicylates almost interchangeably. If we are to lessen the "scientific uncertainties" connected with the studies of salicylate use and Reye's syndrome, may I suggest that we first make a clear statement about ...
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