Results 161 to 170 of about 4,129,928 (338)

Optimal Dose and Safety of Intravenous Favipiravir in Hospitalized Patients With COVID‐19: A Dose‐Escalating, Randomized Controlled Phase Ib Study

Clinical Pharmacology &Therapeutics, EarlyView.
AGILE (NCT04746183) is a Phase Ib/IIa platform, evaluating candidates to treat COVID‐19. Candidate Specific Trial 6 evaluated the safety and optimal dose of a novel intravenous formulation of favipiravir in a dose‐escalating, open‐label, randomized, controlled, Bayesian adaptive Phase Ib trial.
Tim Rowland, Richard FitzGerald, Elizabeth Challenger, Laura Dickinson, Laura J. Else, Lauren Walker, Colin Hale, Victoria Shaw, Callum Kelly, Rebecca Lyon, Jennifer Gibney, Karim Dhamani, Margaret Irwin, Yvanne Enever, Michelle Tetlow, William Wood, Helen Reynolds, Justin Chiong, Orod Osanlou, Henry Pertinez, Katie Bullock, William Greenhalf, Andrew Owen, David G. Lalloo, Michael Jacobs, Julian A. Hiscox, Thomas Jaki, Pavel Mozgunov, Geoffrey Saunders, Gareth Griffiths, Saye H. Khoo, Thomas E. Fletcher, on behalf of the AGILE CST‐6 Study Group, Shazaad Ahmad, Christopher J. Edwards, Lesley Dry, Georgie McKenzie, Aleksandra Ros, Michael Stackpoole, Laura Bradley, Karen Jennings‐Wilding, Nicholas Paton, Fred Hayden, Janet Darbyshire, Amy Lucas, Ulrika Lorch, Andrew Freedman, Richard Knight, Steven Julious   +48 more
wiley   +1 more source

Entropy in Exact 2D Navier-Stokes and 3D Burgers Gas Flows. [PDF]

Entropy (Basel)
Broadbridge P.
europepmc   +1 more source

Managers' Sustainability Mindset: The Role of Place Attachment and Absorptive Capacity

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Sustainability mindset among managers is crucial for advancing sustainable development and creating long‐term environmental and social value. This study focuses on middle managers in Indian organizations and explores how place attachment and managerial absorptive capacity affect their sustainability mindset.
Asha K. S. Nair, Tulin Dzhengiz, Som Sekhar Bhattacharyya   +2 more
wiley   +1 more source

Numerical simulation on heat transfer characteristics of a bionic leaf-vein fractal fin heat exchanger. [PDF]

Sci Rep
Wang R, Hou Y, Yu H, Xing M.
europepmc   +1 more source

Active and passive explicit instruction in question‐formulating in higher education

The Curriculum Journal, EarlyView.
Abstract We investigated the impact of explicit instruction on students' question‐formulating skill using a quantitative pre–post design. Surveys were administered to 291 undergraduates from two colleges before and after a dedicated lesson on question formulation. Students' skills were assessed through performance tasks, evaluated with both Bloom's and
Irit Sasson, Sigal Tifferet
wiley   +1 more source

Minimizing frictional irreversibility in a rough-walled tapered bearing with a nanoparticle-enhanced Sutterby lubricant. [PDF]

Sci Rep
Jazza Y, Hashim, Saqib M, Mousa S.
europepmc   +1 more source

Nanoparticles in microdroplets: Recent advances in microfluidic generators for producing functional microbeads

Droplet, EarlyView.
Functional hybrid microbeads with electrical, magnetic, and/or optical responsiveness have emerged as versatile platforms for biotechnology. This review highlights recent advances in microfluidic technologies for producing such microbeads, with a focus on incorporating functional nanoparticles in microdroplet systems.
  Bayinqiaoge, Chengchen Zhang, Shi‐Yang Tang   +2 more
wiley   +1 more source

Experimental Investigation into Stability, Heat Transfer, and Flow Characteristics of TiO₂-SiO₂ Hybrid Nanofluids Under Multiple Influencing Factors. [PDF]

Nanomaterials (Basel)
Wu J, Li Z, Jian W, Ma D.
europepmc   +1 more source

Sheath‐assisted microfluidics for elasto‐inertial manipulation of micro/nanoparticles: From theory to biomedical applications

Droplet, EarlyView.
This review examines sheath‐assisted elasto‐inertial microfluidics, where viscoelastic and inertial forces synergize to manipulate particles. It analyzes the underlying mechanisms, system designs, and biomedical applications, proposing future research to advance high‐precision technologies.
Huan Wang, Yanting Wang, Yibo Cui, Limiao Yin, Jinwen Li, Yanxuan Wu, Piwu Li, Lei Zhao, Xiaowen Huang   +8 more
wiley   +1 more source

Impact of Magnetohydrodynamics on Thermal Mixing Efficiency and Entropy Generation Analysis Passing Through a Micromixer Using Non-Newtonian Nanofluid. [PDF]

Micromachines (Basel)
Tayeb NT, Laouid YAA, Lakhdar A, Mostefa T, Kim SM, Hossain S.   +5 more
europepmc   +1 more source