Results 261 to 270 of about 10,289,048 (317)

SEC‐SAXS/MC Ensemble Structural Studies of the Microtubule Binding Protein Cdt1 Show Monomeric, Folded‐Over Conformations

open access: yesCytoskeleton, EarlyView.
ABSTRACT Cdt1 is a mixed folded protein critical for DNA replication licensing and it also has a “moonlighting” role at the kinetochore via direct binding to microtubules and the Ndc80 complex. However, it is unknown how the structure and conformations of Cdt1 could allow it to participate in these multiple, unique sets of protein complexes.
Kyle P. Smith   +9 more
wiley   +1 more source

Advances in Diclofenac Derivatives: Exploring Carborane‐Substituted N‐Methyl and Nitrile Analogs for Anti‐Cancer Therapy

open access: yesChemMedChem, Accepted Article.
This study explores the anti‐cancer potential of N‐methylated open‐ring derivatives of carborane‐substituted diclofenac analogs. By N‐methylation, the open‐chain form could be trapped and cyclization back to lactam or amidine derivatives was inhibited.
Christoph Selg   +12 more
wiley   +1 more source

Pre‐industrial Use of Bauxite by Late Gothic Goldsmith Masters: Analytical Evidence and Experimental Study

open access: yesChemPlusChem, EarlyView.
First analytical evidence and replication of yet undescribed substantial change in gilding technology in the early modern period ‐ the replacement of imported red clay (bole) with locally available bauxite. Proof of its source ‐ Croatian Minjera, according to a unique find of mineral diaspore.
David Hradil   +3 more
wiley   +1 more source

A self-propelled biohybrid swimmer at low Reynolds number

open access: yesNature Communications, 2014
Brian J. Williams   +3 more
semanticscholar   +1 more source

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