Results 61 to 70 of about 37,077 (265)

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

open access: yesAdvanced Science, EarlyView.
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

Numerical Analysis of Tip Vortex and Cavitation of Elliptic Hydrofoil with NACA 662-415 Cross Section

open access: yes한국해양공학회지, 2018
This paper provides quantification of the effects of the turbulence model and grid refinement on the analysis of tip vortex flows by using the RANS(Reynolds averaged Navier-Stokes) method. Numerical simulations of the tip vortex flows of the NACA 662-415
Il-Ryong Park   +4 more
doaj   +1 more source

Single‐Cell Reveal GALNT7‐Dependent Ferroptosis Suppression as a Mechanism of Immunotherapy Resistance in Non‐Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Integrated clinical and mechanistic analyses identify GALNT7 as a ferroptosis‐suppressive regulator associated with immunotherapy resistance in non‐small cell lung cancer. GALNT7 depletion promotes lipid peroxidation, mitochondrial dysfunction, and ferroptosis, enhances CD8+ T‐cell activation and IFN‐γ production, and sensitizes tumors to PD‐1 blockade,
Jiadi Gan   +11 more
wiley   +1 more source

Time-resolved PIV measurement of influence of upstream roughness on separated and reattached turbulent flows over a forward-facing step

open access: yesAIP Advances, 2018
This study reports an experimental investigation of the effects of upstream roughness on a low Reynolds number turbulent boundary layer over a forward-facing step.
Ali Nematollahi, Mark F. Tachie
doaj   +1 more source

Eco‐Friendly Solvent System for Inkjet Deposition of Wide Bandgap Perovskite Solar Cells Enabling Tandem Integration

open access: yesAdvanced Science, EarlyView.
The fabrication of wide‐bandgap perovskite thin films via green solvents integrated with inkjet printing is developed. Controlled crystallization of the perovskite layer is achieved by optimizing ink formulation and additive engineering, enabling power conversion efficiencies above 17% for single junctions and 28% for perovskite/silicon tandem solar ...
Uma Kousalya Dangudubiyyam   +12 more
wiley   +1 more source

Analysis of Pseudo-Turbulence Flow Induced by Bubble Periodic Formation in Non-Newtonian Fluids [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2018
Laser Doppler Velocimetry (LDV) has been employed to determine pseudo-turbulence characteristics of the flow field around bubble train forming in non-Newtonian caboxymethylcellulose (CMC) aqueous solution at low gas flow rate condition.
Wenyuan Fan, Xiao Hong Yin
doaj  

Efficient Adsorption‐Based Direct Air Capture Via Triply Periodic Minimal Surface Architectures

open access: yesAdvanced Science, EarlyView.
Architected triply periodic minimal surface (TPMS) contactors reshape direct air capture by replacing straight‐channel diffusion limits with convection‐enhanced CO2 transport. Chaotic advection thins boundary layers and exposes fast adsorption sites, enabling 70%–75% more fast sites, 114% higher productivity, and 51.8% lower energy consumption than ...
Qingyang Shao   +6 more
wiley   +1 more source

Application of Different Turbulence Models Simulating Wind Flow in Complex Terrain: A Case Study for the WindForS Test Site

open access: yesComputation, 2018
A model for the simulation of wind flow in complex terrain is presented based on the Reynolds averaged Navier–Stokes (RANS) equations. For the description of turbulence, the standard k-ε, the renormalization group (RNG) k-ε, and a ...
Hermann Knaus   +3 more
doaj   +1 more source

Reynolds Stress Transport Modelling

open access: yes, 2011
The Reynolds–averaged Navier–Stokes (RANS) approach is the most commonly employed approach in CFD for industrial applications, and is likely to continue to be so for the foreseeable future. The need to handle complex wall-bounded flows, and the need to evaluate large numbers of design variations usually prohibits high-fidelity approaches such as direct
openaire   +2 more sources

CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano   +10 more
wiley   +1 more source

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