Results 41 to 50 of about 720,181 (274)
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Earth and Space Science, 2022 We use a cluster feature data set for the Fast On‐orbit Recording of Transient Events (FORTE) satellite that combines detections from its pixelated Lightning Locating System (LLS), photodiode detector (PDD) and Radio‐Frequency (RF) instrumentation to ...
Michael Peterson
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
CureIt – A Multidisease Predictive System using Machine Learning [PDF]
ITM Web of ConferencesMany contemporary machine learning approaches perform well in predictive analytics on large datasets from many sectors. While predictive analytics in healthcare remains an ambitious goal, it has the potential to enable healthcare practitioners to make ...
Mehta Apoorva S. +2 more
doaj +1 more source
Monitoring of Huntington’s Disease Based on Wireless Sensing Technology
Applied Sciences, 2020 Huntington’s disease (HD) is a rare genetic disorder that cannot be cured by current medical techniques. With the development of the disease, the life of patients will become more and more difficult.
Qiyu Zhu +3 more
doaj +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Application of machine learning methods on investigation the effect of interrupted deflector's height and downstream depth changes on energy dissipation at flip bucket spillways [PDF]
Journal of Hydraulic StructuresFlip bucket is a type of energy dissipator structure. Flip buckets can sometimes be improved by adding wedge-shaped deflectors. This research introduced the best height proportion of used deflector on the flip buckets to increase energy dissipation.
Arash Adib +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Machine learning algorithm for improving performance on 3 AQ-screening classification
Communications in Science and Technology, 2019 Autism Spectrum Disorder (ASD) classification using machine learning can help parents, caregivers, psychiatrists, and patients to obtain the results of early detection of ASD.
Taftazani Ghazi Pratama +2 more
doaj +1 more source
Estimation and mapping of pasture biomass in Mongolia using machine learning methods
Geocarto International, 2023 Mongolian pasture plays an essential role in the national economy. Reliable pasture biomass estimation is indispensable to support the agricultural sector and also sustainable livelihood in the country.
Enkhmanlai Amarsaikhan +4 more
doaj +1 more source