Results 121 to 130 of about 79,904 (133)

Ginsenoside Rg1 Attenuates Chronic Sleep Deprivation-Induced Hippocampal Mitochondrial Dysfunction and Improves Memory by the AMPK-SIRT3 Pathway.

Journal of Agricultural and Food Chemistry
Ginsenoside Rg1 (Rg1) is the main bioactive ginseng component. This study investigates the effects of Rg1 on cognitive deficits triggered by chronic sleep deprivation stress (CSDS) and explores its underlying mechanisms.
Ning Jiang, CA Yao, Yiwen Zhang, Xinran Sun, M. I. Choudhary, Xinmin Liu   +5 more
semanticscholar   +1 more source

Ginsenoside Rg1 improves Alzheimer's disease by regulating oxidative stress, apoptosis, and neuroinflammation through Wnt/GSK‐3β/β‐catenin signaling pathway

Chemical Biology and Drug Design, 2022
Alzheimer's disease (AD) is a chronic neurodegenerative disorder that can cause cognitive impairment. Ginsenoside Rg1 (Rg1) has a significant neuroprotective effect on animals with memory impairment.
Yi Yang, Limei Wang, Caijun Zhang, Yuqian Guo, Jintao Li, Chao Wu, Jianlin Jiao, Hong Zheng   +7 more
semanticscholar   +1 more source

Ginsenoside Rg1 Suppresses Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway to Alleviate Chronic Atrophic Gastritis In Vitro and In Vivo.

Journal of Agricultural and Food Chemistry
Chronic atrophic gastritis (CAG) is characterized by the loss of gastric glandular cells, which are replaced by the intestinal-type epithelium and fibrous tissue. Ginsenoside Rg1 (Rg1) is the prevalent ginsenoside in ginseng, with a variety of biological
Zehua Zhou, Cheng Hu, Bo Cui, Lisha You, Rui An, Kun Liang, Xinhong Wang   +6 more
semanticscholar   +1 more source

Ginsenoside Rg1 ameliorates sepsis‐induced acute kidney injury by inhibiting ferroptosis in renal tubular epithelial cells

Journal of Leukocyte Biology, 2022
Acute kidney injury (AKI) represents a prevailing complication of sepsis, and its onset involves ferroptosis. Ginsenoside Rg1 exerts a positive effect on kidney diseases. This study explored the action of ginsenoside Rg1 in sepsis‐induced AKI (SI‐AKI) by
Jun Guo, Rong Wang, Fei Min
semanticscholar   +1 more source

Ginsenoside Rg1 improved diabetes through regulating the intestinal microbiota in high-fat diet and streptozotocin-induced type 2 diabetes rats.

Journal of food biochemistry, 2022
Ginsenoside Rg1 is the active ingredient of the plant named genus Panax (ginseng), which exhibited significant bioactivities, including anti-inflammatory, antioxidation, and anti-diabetic effects.
Man Peng, Liming Wang, Hui Su, Lei Zhang, Yue Yang, Le Sun, Yi Wu, Lei Ran, Sida Liu, Mingxiao Yin, Shude Li, W. Chunyu   +11 more
semanticscholar   +1 more source

Rosmarinic acid in combination with ginsenoside Rg1 suppresses colon cancer metastasis via co-inhition of COX-2 and PD1/PD-L1 signaling axis

Acta Pharmacologica Sinica, 2023
Huan Liu, Rui Deng, Chengshu Zhu, H. Han, Gang-Fan Zong, Lang Ren, Peng Cheng, Zhong-Hong Wei, Yang Zhao, Su-yun Yu, Yin Lu   +10 more
semanticscholar   +1 more source

Ginsenoside Rg1 modulates PI3K/AKT pathway for enhanced osteogenesis via GPER.

Phytomedicine, 2023
Zhongjing Jiang, Linhua Deng, Mengjun Li, Emmanuel Alonge, Yanling Wang, Yunjia Wang   +5 more
semanticscholar   +1 more source

Ginsenoside Rg1 treats ischemic stroke by regulating CKLF1/CCR5 axis-induced neuronal cell pyroptosis.

Phytomedicine, 2023
Junpeng Long, Yang Sun, Shasha Liu, Chen Chen, Qian Yan, Yuting Lin, Zhao Zhang, Shifeng Chu, Yantao Yang, Songwei Yang, Mei-yu Lin, Xuan Liu, Jinping Liang, Naihong Chen, Qidi Ai   +14 more
semanticscholar   +1 more source

Ginsenoside Rg1 attenuates lipopolysaccharide-induced chronic liver damage by activating Nrf2 signaling and inhibiting inflammasomes in hepatic cells.

Journal of Ethnopharmacology
Hui-Lan Zhou, Yan Liu, Yong Su, Pengmin Ji, L. Kong, Ran Sun, Duoduo Zhang, Hanyang Xu, Weiping Li, Weizu Li   +9 more
semanticscholar   +1 more source

Ginsenoside Rg1 alleviates chronic inflammation-induced neuronal ferroptosis and cognitive impairments via regulation of AIM2 - Nrf2 signaling pathway.

Journal of Ethnopharmacology
L. Kong, Yan Liu, Jingwei Li, Yanyan Wang, Pengmin Ji, Qifeng Shi, Min Han, Hanyang Xu, Weiping Li, Weizu Li   +9 more
semanticscholar   +1 more source