Results 121 to 130 of about 72,962 (133)

Ginsenoside Rg1/ADSCs supplemented with hyaluronic acid as the matrix improves rabbit temporomandibular joint osteoarthrosis.

Biotechnology & Genetic Engineering Reviews, 2023
OBJECTIVE To investigate whether and how ginsenoside Rg1/ADSCs supplemented with hyaluronic acid as the matrix can improve rabbit temporomandibular joint osteoarthrosis.
Yanwei Guo, Tingyu Tian, Shimao Yang, Yuping Cai   +3 more
semanticscholar   +1 more source

Ginsenoside Rg1 improves Alzheimer's disease by regulating oxidative stress, apoptosis, and neuroinflammation through Wnt/GSK‐3β/β‐catenin signaling pathway

Chemical Biology and Drug Design, 2022
Alzheimer's disease (AD) is a chronic neurodegenerative disorder that can cause cognitive impairment. Ginsenoside Rg1 (Rg1) has a significant neuroprotective effect on animals with memory impairment.
Yi Yang, Limei Wang, Caijun Zhang, Yuqian Guo, Jintao Li, Chao Wu, Jianlin Jiao, Hong Zheng   +7 more
semanticscholar   +1 more source

Ginsenoside Rg1 ameliorates sepsis‐induced acute kidney injury by inhibiting ferroptosis in renal tubular epithelial cells

Journal of Leukocyte Biology, 2022
Acute kidney injury (AKI) represents a prevailing complication of sepsis, and its onset involves ferroptosis. Ginsenoside Rg1 exerts a positive effect on kidney diseases. This study explored the action of ginsenoside Rg1 in sepsis‐induced AKI (SI‐AKI) by
Jun Guo, Rong Wang, Fei Min
semanticscholar   +1 more source

Ginsenoside Rg1 improved diabetes through regulating the intestinal microbiota in high-fat diet and streptozotocin-induced type 2 diabetes rats.

Journal of food biochemistry, 2022
Ginsenoside Rg1 is the active ingredient of the plant named genus Panax (ginseng), which exhibited significant bioactivities, including anti-inflammatory, antioxidation, and anti-diabetic effects.
Man Peng, Liming Wang, Hui Su, Lei Zhang, Yue Yang, Le Sun, Yi Wu, Lei Ran, Sida Liu, Mingxiao Yin, Shude Li, W. Chunyu   +11 more
semanticscholar   +1 more source

Anti-inflammatory effect of ginsenoside Rg1 on LPS-induced septic encephalopathy and associated mechanism.

Current Neurovascular Research, 2022
BACKGROUND Sepsis frequently occurs in patients after infection and is highly associated with death. Septic encephalopathy is characterized by dysfunction of the central nervous system, of which the root cause is a systemic inflammatory response.
Yuan Chen, Miaomiao Chi, Xinyue Qiao, Jiabing Wang, Yong Jin   +4 more
semanticscholar   +1 more source

Ginsenoside Rg1 Attenuates Chronic Sleep Deprivation-Induced Hippocampal Mitochondrial Dysfunction and Improves Memory by the AMPK-SIRT3 Pathway.

Journal of Agricultural and Food Chemistry
Ginsenoside Rg1 (Rg1) is the main bioactive ginseng component. This study investigates the effects of Rg1 on cognitive deficits triggered by chronic sleep deprivation stress (CSDS) and explores its underlying mechanisms.
Ning Jiang, CA Yao, Yiwen Zhang, Xinran Sun, M. I. Choudhary, Xinmin Liu   +5 more
semanticscholar   +1 more source

Ginsenoside Rg1 Suppresses Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway to Alleviate Chronic Atrophic Gastritis In Vitro and In Vivo.

Journal of Agricultural and Food Chemistry
Chronic atrophic gastritis (CAG) is characterized by the loss of gastric glandular cells, which are replaced by the intestinal-type epithelium and fibrous tissue. Ginsenoside Rg1 (Rg1) is the prevalent ginsenoside in ginseng, with a variety of biological
Zehua Zhou, Cheng Hu, Bo Cui, Lisha You, Rui An, Kun Liang, Xinhong Wang   +6 more
semanticscholar   +1 more source

Ginsenoside Rg1 modulates intestinal microbiota and supports re-generation of immune cells in dexamethasone-treated mice.

Acta Microbiologica et Immunologica Hungarica, 2022
Ginsenoside Rg1 is one of the major ginsenosides found in roots of Panax ginseng and Panax notoginseng. Ginsenoside Rg1 is known to possess various biological activities including immunity enhancement activity.
S. Yousuf, He Liu, Zhang Yingshu, Danishi Zahid, Hassan Ghayas, Ming Li, Yanl Ding, Wenzhe Li   +7 more
semanticscholar   +1 more source

Ginsenoside Rg1 suppresses paraquat‐induced epithelial cell senescence by enhancing autophagy in an ATG12‐dependent manner

Environmental Toxicology, 2022
Paraquat (PQ), as a widely used herbicide, is highly toxic to human. PQ‐induced pulmonary fibrosis is the main reason for respiratory failure and death.
Changbao Huang, Xiang Xue, Nengkai Gong, Jinghan Jiang   +3 more
semanticscholar   +1 more source

Rosmarinic acid in combination with ginsenoside Rg1 suppresses colon cancer metastasis via co-inhition of COX-2 and PD1/PD-L1 signaling axis

Acta Pharmacologica Sinica, 2023
Huan Liu, Rui Deng, Chengshu Zhu, H. Han, Gang-Fan Zong, Lang Ren, Peng Cheng, Zhong-Hong Wei, Yang Zhao, Su-yun Yu, Yin Lu   +10 more
semanticscholar   +1 more source