Results 121 to 130 of about 75,644 (134)

Ginsenoside Rg1 Alleviates Ulcerative Colitis in Obese Mice by Regulating the Gut Microbiota-Lipid Metabolism-Th1/Th2/Th17 Cells Axis.

Journal of Agricultural and Food Chemistry, 2023
Ginsenoside Rg1 (G-Rg1) has various pharmacological properties including antiobesity, immunomodulatory, and anti-inflammatory effects. This study aimed to explore the therapeutic effects and underlying mechanisms of G-Rg1 on colitis complicated by ...
Youbao Zhong, Qiuping Xiao, Jiaqi Huang, Songren Yu, Liling Chen, Qi Wan, Zheyan Zhang, Lin Luo, Lizhao Song, Haimei Zhao, Wen Zhou, Duanyong Liu   +11 more
semanticscholar   +1 more source

Ginsenoside Rg1 activates brown adipose tissue to counteract obesity in high-fat diet-fed mice by regulating gut microbes and bile acid composition.

Food & Function, 2023
Obesity is a global health problem strongly linked to gut microbes and their metabolites. In this study, ginsenoside Rg1 (Rg1) reduced lipid droplet size and hepatic lipid accumulation by activating uncoupling protein 1 expression in brown adipose tissue
Yize Liu, Zheng-Yun Jin, Junxia Wang, Danqi Wang, Hongye Liu, Dongxu Li, Junfei Zhu, Zhao-Bo Luo, Shengzhong Han, Shuangyan Chang, Liu-Hui Yang, Jin-Dan Kang, Lin-Hu Quan   +12 more
semanticscholar   +1 more source

Ginsenoside Rg1/ADSCs supplemented with hyaluronic acid as the matrix improves rabbit temporomandibular joint osteoarthrosis

Biotechnology & Genetic Engineering Reviews, 2023
Objective: To investigate whether and how ginsenoside Rg1/ADSCs supplemented with hyaluronic acid as the matrix can improve rabbit temporomandibular joint osteoarthrosis.
Yanwei Guo, Tingyu Tian, Shimao Yang, Yuping Cai   +3 more
semanticscholar   +1 more source

Ginsenoside Rg1 improves Alzheimer's disease by regulating oxidative stress, apoptosis, and neuroinflammation through Wnt/GSK‐3β/β‐catenin signaling pathway

Chemical Biology and Drug Design, 2022
Alzheimer's disease (AD) is a chronic neurodegenerative disorder that can cause cognitive impairment. Ginsenoside Rg1 (Rg1) has a significant neuroprotective effect on animals with memory impairment.
Yi Yang, Limei Wang, Caijun Zhang, Yuqian Guo, Jintao Li, Chao Wu, Jianlin Jiao, Hong Zheng   +7 more
semanticscholar   +1 more source

Ginsenoside Rg1 ameliorates sepsis‐induced acute kidney injury by inhibiting ferroptosis in renal tubular epithelial cells

Journal of Leukocyte Biology, 2022
Acute kidney injury (AKI) represents a prevailing complication of sepsis, and its onset involves ferroptosis. Ginsenoside Rg1 exerts a positive effect on kidney diseases. This study explored the action of ginsenoside Rg1 in sepsis‐induced AKI (SI‐AKI) by
Jun Guo, Rong Wang, Fei Min
semanticscholar   +1 more source

Ginsenoside Rg1 improved diabetes through regulating the intestinal microbiota in high-fat diet and streptozotocin-induced type 2 diabetes rats.

Journal of food biochemistry, 2022
Ginsenoside Rg1 is the active ingredient of the plant named genus Panax (ginseng), which exhibited significant bioactivities, including anti-inflammatory, antioxidation, and anti-diabetic effects.
Man Peng, Liming Wang, Hui Su, Lei Zhang, Yue Yang, Le Sun, Yi Wu, Lei Ran, Sida Liu, Mingxiao Yin, Shude Li, W. Chunyu   +11 more
semanticscholar   +1 more source

Ginsenoside Rg1 Attenuates Chronic Sleep Deprivation-Induced Hippocampal Mitochondrial Dysfunction and Improves Memory by the AMPK-SIRT3 Pathway.

Journal of Agricultural and Food Chemistry
Ginsenoside Rg1 (Rg1) is the main bioactive ginseng component. This study investigates the effects of Rg1 on cognitive deficits triggered by chronic sleep deprivation stress (CSDS) and explores its underlying mechanisms.
Ning Jiang, CA Yao, Yiwen Zhang, Xinran Sun, M. I. Choudhary, Xinmin Liu   +5 more
semanticscholar   +1 more source

Ginsenoside Rg1 Suppresses Pyroptosis via the NF-κB/NLRP3/GSDMD Pathway to Alleviate Chronic Atrophic Gastritis In Vitro and In Vivo.

Journal of Agricultural and Food Chemistry
Chronic atrophic gastritis (CAG) is characterized by the loss of gastric glandular cells, which are replaced by the intestinal-type epithelium and fibrous tissue. Ginsenoside Rg1 (Rg1) is the prevalent ginsenoside in ginseng, with a variety of biological
Zehua Zhou, Cheng Hu, Bo Cui, Lisha You, Rui An, Kun Liang, Xinhong Wang   +6 more
semanticscholar   +1 more source

Anti-inflammatory effect of ginsenoside Rg1 on LPS-induced septic encephalopathy and associated mechanism.

Current Neurovascular Research, 2022
BACKGROUND Sepsis frequently occurs in patients after infection and is highly associated with death. Septic encephalopathy is characterized by dysfunction of the central nervous system, of which the root cause is a systemic inflammatory response.
Yuan Chen, Miaomiao Chi, Xinyue Qiao, Jiabing Wang, Yong Jin   +4 more
semanticscholar   +1 more source

Ginsenoside Rg1 modulates intestinal microbiota and supports re-generation of immune cells in dexamethasone-treated mice.

Acta Microbiologica et Immunologica Hungarica, 2022
Ginsenoside Rg1 is one of the major ginsenosides found in roots of Panax ginseng and Panax notoginseng. Ginsenoside Rg1 is known to possess various biological activities including immunity enhancement activity.
S. Yousuf, He Liu, Zhang Yingshu, Danishi Zahid, Hassan Ghayas, Ming Li, Yanl Ding, Wenzhe Li   +7 more
semanticscholar   +1 more source