Results 41 to 50 of about 79,904 (133)

Ginsenoside Rg1 attenuates dextran sodium sulfate-induced ulcerative colitis in mice.

Physiological Research, 2023
Ulceration colitis (UC) is a chronic and recurrent inflammatory disorder in the gastro-intestinal tract. The purpose of our study is to explore the potential mechanisms of ginsenoside Rg1 (GS Rg1) on dextran sulfate sodium (DSS)-induced colitis in mice ...
Y. Chen, Q. Zhang, L. Sun, H. Liu, J. Feng, J. Li, Z. Wang   +6 more
semanticscholar   +1 more source

Ginsenoside Rg1 improves anti-tumor efficacy of adoptive cell therapy by enhancing T cell effector functions

Blood Science, 2023
Adoptive cell therapy (ACT) has emerged with remarkable efficacies for tumor immunotherapy. Chimeric antigen receptor (CAR) T cell therapy, as one of most promising ACTs, has achieved prominent effects in treating malignant hematological tumors. However,
Yue Liu, Lingna An, Chengfei Yang, Xiaoqi Wang, Ruihao Huang, Xi Zhang   +5 more
semanticscholar   +1 more source

Ginsenoside Rg1 Regulates Immune Microenvironment and Neurological Recovery After Spinal Cord Injury Through MYCBP2 Delivery via Neuronal Cell‐Derived Extracellular Vesicles

Advancement of science
Spinal cord injury (SCI) is a severe neurological condition that frequently leads to significant sensory, motor, and autonomic dysfunction. This study sought to delineate the potential mechanistic underpinnings of extracellular vesicles (EVs) derived ...
Yuluo Rong, Jiaxing Wang, Tao Hu, Zhongming Shi, Chuandong Lang, Wei Liu, Weihua Cai, Yongjin Sun, Feng Zhang, Wenzhi Zhang   +9 more
semanticscholar   +1 more source

Rg1 alleviates oxidative stress and spermatogonium apoptosis in D-gal-induced testicular toxicity by activating Akt

Redox Report, 2023
Objectives: High reactive oxygen species (ROS) levels lead to cell death, and the testes are among the most vulnerable organs to oxidative damage. Rg1, an active ingredient extracted from the natural medicine ginseng, has potential anti-inflammatory ...
Ziling Wang, Kunhang Du, Jiying Hou, Han Xiao, Ling Hu, Xiongbin Chen, Lu Wang, Yaping Wang   +7 more
semanticscholar   +1 more source

Ginsenoside Rg1 Improves Inflammation and Autophagy of the Pancreas and Spleen in Streptozotocin-Induced Type 1 Diabetic Mice

International Journal of Endocrinology, 2023
Background Ginsenoside Rg1 (Rg1) is one of the key bioactive components of the precious Traditional Chinese Medicine that has been used to treat diabetes in China. Ginsenosides have been reported to protect diabetics from tissue damage, inflammation, and
Yi Zong, Weihua Yu, Hanghang Hong, Zhiqiang Zhu, W. Xiao, Kewu Wang, Guoqiang Xu   +6 more
semanticscholar   +1 more source

The protective effect of ginsenoside Rg1 against sepsis-induced lung injury through PI3K-Akt pathway: insights from molecular dynamics simulation and experimental validation

Scientific Reports
Sepsis-induced acute lung injury (SALI) poses a significant threat with high incidence and mortality rates. Ginsenoside Rg1 (GRg1), derived from Ginseng in traditional Chinese medicine, has been found to reduce inflammation and protect lung epithelial ...
Kaiqiang Zhong, Yingui Huang, Rui Chen, Qiusha Pan, Jun Li, Xiaotu Xi   +5 more
semanticscholar   +1 more source

Ginsenoside Rg1 Ameliorates Pancreatic Injuries via the AMPK/mTOR Pathway in vivo and in vitro

Diabetes, Metabolic Syndrome and Obesity : Targets and Therapy, 2023
Background The main propanaxatriol-type saponin found in ginseng (Panax ginseng C. A. Mey), ginsenoside Rg1 (G-Rg1), has bioactivities that include anti-inflammatory, antioxidant, and anti-diabetic properties.
Jin Chen, Guoping Zhu, W. Xiao, Xiaosong Huang, Kewu Wang, Yi Zong   +5 more
semanticscholar   +1 more source

The Effects of Fresh Moringa Leaf Consumption During Pregnancy on Maternal Hemoglobin Level in Southern Ethiopia: Multilevel Analysis of a Comparative Cross-Sectional Study [LETTER]

International Journal of Women's Health, 2023
Ami Febriza,1,2 Hasta Handayani Idrus2 1Department of Physiology, Faculty of Medicine and Health Sciences, Universitas Muhammadiyah Makassar, Makassar, Indonesia; 2Centre for Biomedical Research, Research Organization for Health, National Research and ...
Febriza A, Idrus HH
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Effects of Ginsenoside Rg1 on the Biological Behavior of Human Amnion-Derived Mesenchymal Stem/Stromal Cells (hAD-MSCs)

Stem Cells International, 2023
Ginsenoside Rg1 (Rg1) is purified from ginseng with various pharmacological effects, which might facilitate the biological behavior of human amnion-derived mesenchymal stem/stromal cells (hAD-MSCs). This study is aimed at investigating the effects of Rg1
Lizhen Ling, Han Shu, Yubin Huang, Jiying Hou, Yuanyuan Hua   +4 more
semanticscholar   +1 more source

New Therapeutic Approaches to and Mechanisms of Ginsenoside Rg1 against Neurological Diseases

Cells, 2022
Neurological diseases, including Parkinson’s disease (PD), Alzheimer’s disease (AD), Huntington’s disease (HD), stroke, cerebral infarction, ischemia-reperfusion injury, depression and, stress, have high incidence and morbidity and often lead to ...
Yang Sun, Yantao Yang, Shasha Liu, Songwei Yang, Chen Chen, Mei-yu Lin, Qi Zeng, Junpeng Long, Jiao Yao, Fan Yi, Lei Meng, Qidi Ai, Naihong Chen   +12 more
semanticscholar   +1 more source