Results 51 to 60 of about 79,904 (133)

Ginsenoside Rg1 Reduced Microglial Activation and Mitochondrial Dysfunction to Alleviate Depression-Like Behaviour Via the GAS5/EZH2/SOCS3/NRF2 Axis

Molecular Neurobiology, 2022
Ginsenoside Rg1 is the principal active ingredient in ginseng. The antidepressant effects of Rg1 have been validated; however, the specific underlying mechanism of this effect needs further research.
Junnan Li, Wei Gao, Zhonghui Zhao, Yannan Li, Lixuan Yang, Wei Wei, Feifei Ren, Yang Li, Yao Yu, Wenzhe Duan, Jingchun Li, Baoan Dai, Rongjuan Guo   +12 more
semanticscholar   +1 more source

Nephroprotective effect of Ginsenoside Rg1 in lipopolysaccharide-induced sepsis in mice through the SIRT1/NF-κB signaling.

Folia Histochemica et Cytobiologica
INTRODUCTION During sepsis, the kidney is one of the most vulnerable organs. Sepsis-associated acute kidney injury (S-AKI) is hallmarked by renal inflammation, apoptosis, and oxidative injury.
Yadan Hu, Chao Xiang, Dong Zhang, Fang Zhou, Dede Zhang   +4 more
semanticscholar   +1 more source

Ginsenoside Rg1 interferes with the progression of diabetic osteoporosis by promoting type H angiogenesis modulating vasculogenic and osteogenic coupling

Frontiers in Pharmacology, 2022
Ginsenoside Rg1 (Rg1) has been demonstrated to have antidiabetic and antiosteoporotic activities. The aim of this study was to investigate the protective effect of Rg1 against diabetic osteoporosis and the underlying mechanism.
Wenhui Chen, Xinyan Jin, Tingli Wang, Ruibin Bai, Jun Shi, Yunxia Jiang, Simin Tan, Ruijie Wu, Shiqi Zeng, Hongxiang Zheng, Hongyan Jia, Shuanglei Li   +11 more
semanticscholar   +1 more source

Ginsenoside Rg1 Induces Autophagy in Colorectal Cancer through Inhibition of the Akt/mTOR/p70S6K Pathway

Journal of Microbiology and Biotechnology
This study aimed to elucidate the anti-colon cancer mechanism of ginsenoside Rg1 in vitro and in vivo. Cell viability rate was detected using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) tetrazolium assay.
Ruiqi Liu, Bin Zhang, Shuting Zou, Li Cui, Lin Lin, Lingchang Li   +5 more
semanticscholar   +1 more source

Hepatoprotective Mechanism of Ginsenoside Rg1 against Alcoholic Liver Damage Based on Gut Microbiota and Network Pharmacology

Oxidative Medicine and Cellular Longevity, 2022
Alcoholic liver disease (ALD) is a major public health problem worldwide, which needs to be effective prevention. Ginsenoside Rg1 (GRg1), a bioactive ingredient extracted from ginseng, has benefit effects on health. In this study, 11 potential targets of
Ting Xia, Bin Fang, Chaoyan Kang, Yuxuan Zhao, Xiao Qiang, Xiaodong Zhang, Yiming Wang, Tian Zhong, Jianbo Xiao, Min Wang   +9 more
semanticscholar   +1 more source

Ginsenoside Rg1 ameliorates psoriasis-like skin lesions by suppressing proliferation and NLRP3 inflammasomes in keratinocytes.

Journal of food biochemistry, 2022
As a common chronic skin disease, psoriasis is characterized by the involvement of congenital acquired inflammatory immune diseases. In the study, our results indicated the effect of ginsenoside Rg1 on psoriasis-like skin and the potential protection ...
Jingyi Mao, Xin Ma, Jiong Zhu, Huimin Zhang   +3 more
semanticscholar   +1 more source

Effect of ginsenoside Rg1 on hematopoietic stem cells in treating aplastic anemia in mice via MAPK pathway

World Journal of Stem Cells
BACKGROUND Aplastic anemia (AA) presents a significant clinical challenge as a life-threatening condition due to failure to produce essential blood cells, with the current therapeutic options being notably limited. AIM To assess the therapeutic potential
Jin-Bo Wang, Ming-Wei Du, Yan Zheng
semanticscholar   +1 more source

Association Between Endometritis and Endometrial Polyp: A Mendelian Randomization Study

International Journal of Women's Health, 2023
Longlong Wei,1,2 Yan Zhao,2 Siyue Xu,2 Cuilian Zhang1,2 1Department of Reproductive Medicine Center, People’s Hospital of Zhengzhou University, Zhengzhou, Henan, People’s Republic of China; 2Department of Reproductive Medicine Center, Henan Provincial ...
Wei L, Zhao Y, Xu S, Zhang C
doaj  

A new screening of preterm birth in gestation with short cervix after pessary plus progesterone [PDF]

Revista Brasileira de Ginecologia e Obstetrícia
Objective This study aims to create a new screening for preterm birth < 34 weeks after gestation with a cervical length (CL) ≤ 30 mm, based on clinical, demographic, and sonographic characteristics.
Marcelo Santucci França, Valter Lacerda de Andrade Jr., Alan Roberto Hatanaka, Roberto Santos, Francisco Herlanio Costa Carvalho, Maria Laura Costa, Gabriela Ubeda Santucci França, Rosiane Mattar, Ben Willem Mol, Antonio Fernandes Moron, Rodolfo de Carvalho Pacagnella   +10 more
doaj   +1 more source

Quality monitoring of Shenmai injection by HPLC pharmacodynamic fingerprinting. [PDF]

BMC Chem, 2023
Yang G, Li S, Sun X, Lv Y, Huang H.
europepmc   +1 more source