Results 221 to 230 of about 24,061,183 (328)

Efficacy and Safety of Guselkumab in Participants with Active Psoriatic Arthritis After Inadequate Response to One Prior Tumor Necrosis Factor Inhibitor: Week‐24 Results of the Phase 3, Randomized, Placebo‐Controlled SOLSTICE Study

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Evaluate the efficacy and safety of guselkumab, an interleukin‐23p19‐subunit inhibitor, in participants with active psoriatic arthritis (PsA) and inadequate response (inadequate efficacy and/or intolerance) to one prior tumor necrosis factor inhibitor (TNFi‐IR).
Alexis Ogdie   +12 more
wiley   +1 more source

Development and validation of a high-resolution hyperspectral imaging system for the retina. [PDF]

open access: yesJ Biomed Opt
Tran MH   +6 more
europepmc   +1 more source

Dried biofluid droplet morphologies for automated and scalable disease classification

open access: yesDroplet, EarlyView.
For the first time, disease‐specific fingerprints of diabetes and influenza are revealed from dried biofluid droplet morphologies. Using automated droplet detection, texture analysis, and interpretable machine learning, this scalable workflow transforms endpoint droplet patterns into diagnostic biomarkers for point‐of‐care healthcare applications ...
Anusuya Pal   +5 more
wiley   +1 more source

Spatiotemporal cellular dynamics of the notochord shape intervertebral disc morphogenesis in the mouse embryo through apoptosis and proliferation

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The notochord is a midline structure essential for vertebrate embryogenesis, contributing to the development of the nervous system, digestive tract, and vertebral column. In particular, notochord signaling is indispensable for proper patterning and coordinated development of alternating vertebrae and intervertebral discs (IVDs ...
Julie Warin   +5 more
wiley   +1 more source

Mosaic activation of the zebrafish hsp70l heat shock promoter: Implications for interpreting transgenes

open access: yesDevelopmental Dynamics, EarlyView.
Abstract Background The promoters and enhancers of heat shock genes, such as the 1.5‐kb promoter of the zebrafish hsp70l gene, are valuable tools for temporal activation of transgenes. It has been widely purported that heat shock treatments result in ubiquitous expression of hsp70l‐driven transgenes.
Jong‐Su Park, Xiangyun Wei
wiley   +1 more source

Sustainable Live Sound Monitoring and Classification System Enabled by a Triboelectric Nanogenerator and Machine Learning Techniques

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
A high‐performance Triboelectric Nanogenerator (TENG) acoustic sensor using polyimine/graphite polypropylene (PI/GP) was developed for real‐time, sustainable sound monitoring and classification. The self‐powered device delivers 25.67 μW output power, 92.7% accuracy with MobileNet V1, and powers a wireless transmission circuit, demonstrating dual ...
Majid Haji Bagheri   +8 more
wiley   +1 more source

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