Results 121 to 130 of about 118,582 (236)

Quantifying skin microvascular function responses to distinct forms of heat stress in humans using optical coherence tomography

open access: yesExperimental Physiology, EarlyView.
Abstract Optical coherence tomography (OCT) enables visualization and quantification of the cutaneous microvasculature, yet no study has compared responses to distinct forms of heating in humans. We hypothesized that local skin heating (LH) would evoke larger responses in microvascular diameter, velocity, flow and density than passive whole‐body ...
Kristanti W. Wigati   +5 more
wiley   +1 more source

Passive heat therapy is feasible but does not affect cardiometabolic health outcomes in persons with spinal cord injury – a pilot study

open access: yesExperimental Physiology, EarlyView.
Abstract Passive heat therapy can improve cardiometabolic health outcomes in some clinical populations, making it a potential therapeutic tool for individuals with spinal cord injury (SCI), who exhibit elevated cardiometabolic disease risk and face barriers to physical activity.
Sven P. Hoekstra   +6 more
wiley   +1 more source

Abcc1 deficiency protects from corticosterone but not cortisol‐induced adiposity and insulin resistance in a sex‐specific manner

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A mouse model of exogenous glucocorticoid (GC) treatment was used to determine (1) if corticosterone induced the same metabolic dysregulation as cortisol, and (2) whether these differences were mediated by the corticosterone‐specific transmembrane exporter Abcc1.
Mhairi A. Paul   +9 more
wiley   +1 more source

Physiological mechanisms underlying enhanced performance with blood flow restriction training: neuromuscular, vascular and metabolic adaptations

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend We investigated how 6 weeks of dynamic knee‐extensor interval training with blood flow restriction (BFR‐leg) and without (CTRL‐leg) impacts performance and its mechanisms using non‐invasive methods. Specifically, we used gold‐standard methods to assess neuromuscular function, vascular function using Doppler ultrasound, and near ...
Colin Lavigne   +5 more
wiley   +1 more source

Human brain pericytes protect the blood–brain barrier from triple‐negative breast cancer cells while promoting tumor aggressiveness

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Abstract The majority of breast cancer‐related deaths result from metastatic progression, especially brain metastasis, associated with the poorest prognosis. Patients with triple‐negative breast cancer (TNBC) are particularly prone to developing brain metastases.
Eloise Happernegg   +11 more
wiley   +1 more source

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