Results 101 to 110 of about 186,413 (290)

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

open access: yesAdvanced Science, EarlyView.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr.   +20 more
wiley   +1 more source

Toward Advanced Degradable Soft Robotics Incorporating Transient Soft Electronics: Materials, Fabrication, and Applications

open access: yesAdvanced Electronic Materials, EarlyView.
Degradable soft robots are gaining attention for applications in various fields such as exploration, healthcare, and security. The integration of transient electronics is essential to enhance their intelligent task‐performing capabilities. This review offers insights into the advancement of soft electronic–robotic systems by providing an overview of ...
Kyung‐Sub Kim   +3 more
wiley   +1 more source

Upconversion Nanoparticles‐Based Multimodal Tumor Therapy Integrating Photoclick‐Induced Aggregation of Gold Nanoparticles and Ceria‐Curcumin Redox Modulation With Inflammation Attenuation Post‐Treatment

open access: yesAggregate, EarlyView.
A multifunctional nanoplatform (USiCeCurAu) integrating UCNPs, AuNPs, CeO2, and TK‐CUR‐TPP enables synergistic PDT, CDT, and mPTT. The AuNPs act as pore lockers, UCNPs convert NIR into UV/Vis emission, which triggers AuNPs aggregation, TPP‐CUR‐mediated mitochondria damage for HSP70 suppression, and CeO2‐enabled dual role in ROS generation and ...
Junyou Li   +8 more
wiley   +1 more source

Blood group O is associated with ARDS development but exhibits lower mortality in the intensive care unit – A retrospective multicentre study

open access: yesEuropean Clinical Respiratory Journal
Background Acute respiratory distress syndrome (ARDS) is a common cause of respiratory failure in the intensive care unit (ICU). Previous studies have suggested that blood group A increases the risk of developing ARDS following sepsis and major trauma ...
Hazem Koozi   +3 more
doaj   +1 more source

From Droplet to Diagnosis: Spatio‐Temporal Pattern Recognition in Drying Biofluids

open access: yesAdvanced Intelligent Systems, EarlyView.
This article integrates machine learning (ML) with the spatio‐temporal evolution of biofluid droplets to reveal how drying and self‐assembly encode distinctive compositional fingerprints. By leveraging textural features and interpretable ML, it achieves robust classification of blood abnormalities with over 95% accuracy.
Anusuya Pal   +2 more
wiley   +1 more source

Down Syndrome in Maternity Care: Mothers' Experiences of Prenatal Screening

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Prenatal screening for Down syndrome (DS) is offered to expectant parents receiving antenatal care in many countries, with an emphasis on providing parents with the opportunity to make informed choices about their pregnancy. We examined experiences of prenatal screening among mothers of children with DS living in England, Scotland, or Wales ...
Tamar Rutter   +5 more
wiley   +1 more source

Relationship between COVID-19 infection and ABO and Rh blood group systems

open access: diamond, 2022
Tuba Damar Çakırca, Tayibe Bal
openalex   +2 more sources

Case Series of Nizon‐Isidor Syndrome by Heterozygous Variants in MED12L With Further Evidence of Mitotic Instability in One Case With Diploid–Triploid Mosaicism

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Nizon‐Isidor syndrome is a rare disorder caused by heterozygous variants in MED12L, with only eight documented cases in the literature. Here, we present three additional cases of this syndrome. Proband 1 was a 7‐year‐old female who presented with developmental delay, right‐leg hemihypertrophy, laryngeal cleft, esotropia, abnormal skin ...
Russell Stewart   +336 more
wiley   +1 more source

Radiation emergency medical countermeasures: Current formulary, identified gaps, and future approaches

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Current radiation medical countermeasures primarily focus on hematopoietic acute radiation syndrome (H‐ARS) using agents like granulocyte colony‐stimulating factor (G‐CSF), granulocyte‐macrophage colony‐stimulating factor (GM‐CSF), and romiplostim, alongside treatments for internal contamination (Prussian blue, diethylenetriamine pentaacetate [DTPA ...
Wen‐Bing Ma   +12 more
wiley   +1 more source

Targeted Proteomics upon Treatment with Tofersen Identifies Novel Response Markers for Superoxide Dismutase 1‐Linked Amyotrophic Lateral Sclerosis

open access: yesAnnals of Neurology, EarlyView.
Objective Tofersen is the first effective and approved therapy for superoxide dismutase 1 (SOD1)‐associated amyotrophic lateral sclerosis (ALS [SOD1‐ALS]). Following treatment with tofersen, neurofilament levels in patients' cerebrospinal fluid (CSF) and serum seem to respond earlier than clinical parameters.
Christina Steffke   +36 more
wiley   +1 more source
abo blood group system
genetics
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environmental health
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