Results 101 to 110 of about 320,436 (348)

The relationship between ABO/rhesus blood groups and type 2 diabetes mellitus in Maghnia, western Algeria

open access: yesSouth African Family Practice, 2011
Background: To determine the relationship between ABO/rhesus (Rh) blood groups and type 2 diabetes mellitus in a western Algerian population. Method: This case-control study was conducted at the Regional Hospital Centre of Maghnia, Tlemcen, from July ...
M. Dali Sahi   +4 more
doaj   +1 more source

The effects of morning preconditioning protocols on testosterone, cortisol and afternoon sprint cycling performance [conference presentation] [PDF]

open access: yes, 2018
Opportunities exist for athletes to undertake morning exercise protocols in an attempt to potentate afternoon performance. Four sub elite track sprint cyclists completed a morning cycling (Cyc) or weights-based protocol (WP) prior to an afternoon cycling
Maulder, Peter S, McDonald, Kerin
core  

Single‐Cell RNA Sequencing of Thyroid Tissues Reveals Pathogenesis of Graves' Disease

open access: yesAdvanced Science, EarlyView.
Using single‐cell RNA sequencing and TCR profiling, this study constructed an immune cell atlas in thyroid tissue of Graves’ disease (GD), revealing dominant IFN‐γ‐secreting CD4+ T cells, expanded Tph and CD11c+ B cells, and enriched T/NK cells. Notably, GD thyroid follicular cells (TFCs) activated γδ T cells, which recruited cDC1 cells, suggesting a ...
Xiaoyi Zhou   +18 more
wiley   +1 more source

Hepatitis B Virus (HBV) and S-Escape Mutants: From the Beginning until Now [PDF]

open access: yes, 2015
Despite of the progress made in vaccine and antiviral therapy development, hepatitis B virus (HBV) infection remains a major health care problem. More than 240 million people are chronically infected worldwide showing differences in the severity of liver
Cuestas, María Luján   +4 more
core   +1 more source

Reprogramming Tumor‐Associated Macrophages via Targeted NAT10 Inhibition to Enhance Colorectal Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study presents the sono‐sensitive nanorobot Sono@NAT10, which targets NAT10 condensates to reprogram tumor‐associated macrophages in colorectal cancer. By reducing the acetylation level of SRSF2 protein and activating HDAC10, Sono@NAT10 promotes M1 polarization, suppresses tumor progression, and strengthens immunotherapy. The approach demonstrates
Jiahao Zhu   +11 more
wiley   +1 more source

Oral application of L-menthol in the heat: From pleasure to performance [PDF]

open access: yes, 2019
When menthol is applied to the oral cavity it presents with a familiar refreshing sensation and cooling mint flavour. This may be deemed hedonic in some individuals, but may cause irritation in others.
Barwood, Martin   +3 more
core  

Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors

open access: yesAdvanced Science, EarlyView.
This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su   +15 more
wiley   +1 more source

Alloimmunization in blood transfusion´s recipients in UH Motol [PDF]

open access: yes, 2017
V této práci se budeme zabývat odpovědí organismu na cizí antigeny, které v našem případě organismus přijímá při podání krevní transfuze pacientovi. Mimo jiné k tomuto procesu může docházet také v těhotenství při přítomnosti rozdílného antigenu matky a ...
Drunecká Veronika
core  

Grow p‐type MoS2 on FeNC for CO2 Sensing in Complex Environments with Intelligent Recognition

open access: yesAdvanced Science, EarlyView.
In situ growth of p‐type MoS2 (p‐MoS2) on N‐ and Fe‐enriched carbon (FeNC) nanosheets allows for detection of carbon dioxide (CO2) fluctuation levels as low as 50 ppm at 25 °C. The induced S vacancies (Svacs) and the modulated electron distribution jointly improved sensing selectivity to CO2. Abstract A wealth of theoretical studies demonstrates p‐type
Yuefeng Gu   +8 more
wiley   +1 more source

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