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The Rh blood group system: a review [PDF]
Blood, 2000 The Rh blood group system is one of the most polymorphic and immunogenic systems known in humans. In the past decade, intense investigation has yielded considerable knowledge of the molecular background of this system. The genes encoding 2 distinct Rh proteins that carry C or c together with either E or e antigens, and the D antigen, have been cloned ...
Neil D. Avent, Marion E. Reid
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A Decade of Progress in the Rh Blood-Group System
New England Journal of Medicine, 1954Significance of f At present it is difficult to assess the practical importance of the antigen, but of its academic importance there can be no doubt.
Fred H. Allen +2 more
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Molecular biology and genetics of the Rh blood group system
Seminars in Hematology, 2000The Rh (Rhesus) blood group system is the most complex of the known human blood group polymorphisms. The expression of its antigens is controlled by a two-component genetic system consisting of RH and RHAG loci, which encode Rh30 polypeptides and Rh50 glycoprotein, respectively.
Jeffrey G Cheng +2 more
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A microplate system for ABO and Rh(D) blood grouping
Transfusion, 1993A microplate system for performing ABO and Rh(D) blood group determinations with a Kemble Kemtek 1000SP liquid handling processor, an Anthos 2001 microplate reader, an IBM Personal System 2 microcomputer, and Sanguin Forma software is described. The performance of this Kemble/Anthos/IBM/Sanguin microplate system for ABO and D grouping was evaluated by ...
K Ilagan, P Birch, A. Chung
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Molecular Biology of the Rh Blood Group System
Journal of Pediatric Hematology/Oncology, 2001Rh molecular biology has made many advances since the first Rh cDNA was cloned in 1990. This review summarizes the current knowledge concerning the molecular basis of Rh antigenicity, D-epitope expression, and the structures of the Rh genes and proteins.
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RH blood group system and molecular basis of Rh-deficiency
Best Practice & Research Clinical Haematology, 1999Rhesus (Rh) antigens are defined by a complex association of membrane polypeptides that are missing or severely deficient from the red cells of rare Rhnull individuals who suffer a clinical syndrome of varying severity characterized by abnormalities of the red cell shape, cation transport and membrane phospholipid organization.
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A New Antibody; Anti-Rh [27] (cE) in the Rh Blood-Group System
Vox Sanguinis, 1965RésuméUn nouvel anti‐sérum du système Rhésus, l'anti‐Rh[27] a été fabriqué par Mme Th., de type Rhésus 1,2,‐3,‐4,5,‐[27] (DCe/DCe) à la suite de transfusions de sang et de grossesses. Le sérum Th contenait également un anti‐Rh3 (E) et un anti‐S qui ont pu être éliminés facilement par absorption avec des érythrocytes Rh:‐[27], L'anti‐Rh[27] s'est ...
PatriciaA. Corcoran +3 more
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2009
Publisher Summary This chapter focuses on the Rh blood group system and this system is second to the ABO system in clinical importance because of the Rh antigens. The Rh antigens are highly immunogenic and the corresponding antibodies can result in hemolytic transfusion reactions and hemolytic disease of the fetus and newborn.
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Publisher Summary This chapter focuses on the Rh blood group system and this system is second to the ABO system in clinical importance because of the Rh antigens. The Rh antigens are highly immunogenic and the corresponding antibodies can result in hemolytic transfusion reactions and hemolytic disease of the fetus and newborn.
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The abundance and organization of polypeptides associated with antigens of the Rh blood group system
Transfusion Medicine, 1991Summary. Twelve murine monoclonal antibodies, which react with human red cells of common Rh phenotype but give weak or negative reactions with Rh null erythrocytes, were used in quantitative binding assays and competitive binding assays to investigate the abundance and organization of polypeptides involved in the expression of antigens of the Rh blood
A. E. G. Kr. von dem Borne +4 more
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Fortschritte in der Erforschung des Rh-Blutgruppensystems
Blut Zeitschrift für die Gesamte Blutforschung, 1961Es wird versucht, einen Uberblick uber die Fortschritte auf dem Gebiete der Erforschung des Rhesus-Blutgruppensystems zu geben. Die gegenwartige Entwicklung der Erkenntnisse scheint zwei einander entgegengesetzte Richtungen zu verfolgen: einerseits werden Antigene zu Komplexantigenen zusammengefast, andererseits die bisher als einheitlich aufgefasten ...
Hollaender L, Gold Er
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