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Blood Types. The ABO System and Rhesus (Rh) Factor Blood Typing: Why do we have blood groups?
Christian Moro
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The Rh blood group system: a review
Blood, 2000The Rh blood group system is one of the most polymorphic and immunogenic systems known in humans. In the past decade, intense investigation has yielded considerable knowledge of the molecular background of this system. The genes encoding 2 distinct Rh proteins that carry C or c together with either E or e antigens, and the D antigen, have been cloned ...
N D, Avent, M E, Reid
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RH blood group system and molecular basis of Rh-deficiency
Best Practice & Research Clinical Haematology, 1999Rhesus (Rh) antigens are defined by a complex association of membrane polypeptides that are missing or severely deficient from the red cells of rare Rhnull individuals who suffer a clinical syndrome of varying severity characterized by abnormalities of the red cell shape, cation transport and membrane phospholipid organization.
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A New Antibody; Anti-Rh [27] (cE) in the Rh Blood-Group System
Vox Sanguinis, 1965RésuméUn nouvel anti‐sérum du système Rhésus, l'anti‐Rh[27] a été fabriqué par Mme Th., de type Rhésus 1,2,‐3,‐4,5,‐[27] (DCe/DCe) à la suite de transfusions de sang et de grossesses. Le sérum Th contenait également un anti‐Rh3 (E) et un anti‐S qui ont pu être éliminés facilement par absorption avec des érythrocytes Rh:‐[27], L'anti‐Rh[27] s'est ...
P, Keith +3 more
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Advance in the Rh blood group system.
Nihon hoigaku zasshi = The Japanese journal of legal medicine, 1998The Rh blood group antigens are associated with non-glycosylated red blood cell membrane proteins encoded by two closely related genes, RHD and RHCE. Both RH genes have 10 exons and the open reading frames of their transcripts are composed of 1251 nucleotides.
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2009
Publisher Summary This chapter focuses on the Rh blood group system and this system is second to the ABO system in clinical importance because of the Rh antigens. The Rh antigens are highly immunogenic and the corresponding antibodies can result in hemolytic transfusion reactions and hemolytic disease of the fetus and newborn.
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Publisher Summary This chapter focuses on the Rh blood group system and this system is second to the ABO system in clinical importance because of the Rh antigens. The Rh antigens are highly immunogenic and the corresponding antibodies can result in hemolytic transfusion reactions and hemolytic disease of the fetus and newborn.
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Molecular Biology of the Rh Blood Group System
Journal of Pediatric Hematology/Oncology, 2001Rh molecular biology has made many advances since the first Rh cDNA was cloned in 1990. This review summarizes the current knowledge concerning the molecular basis of Rh antigenicity, D-epitope expression, and the structures of the Rh genes and proteins.
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