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Rhabdomyolysis is caused by the breakdown and necrosis of muscle tissue and the release of intracellular content into the blood stream. There are multiple and diverse causes of rhabdomyolysis but central to the pathophysiology is the destruction of the sarcolemmal membrane and release of intracellular components into the systemic circulation.
Cabral, Brian Michael I +3 more
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Virus-induced myopathy can be an important cause of life-threatening rhabdomyolysis. We report the case of a 30-year-old patient who developed rhabdomyolysis and acute renal failure in association with herpes simplex virus infection.
Sucharitha, Shanmugam +1 more
core +4 more sources
ABSTRACT Muscle injury resulting in markedly elevated creatine kinase levels is termed rhabdomyolysis . The muscle damage can occur because of direct or indirect trauma, or it can be related to the use of certain medications, toxins, illicit drugs, or the presence of ...
Kavita M, Grover, Naganand, Sripathi
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Muscle and Nerve, 2002
AbstractRhabdomyolysis, a syndrome of skeletal muscle breakdown with leakage of muscle contents, is frequently accompanied by myoglobinuria, and if sufficiently severe, acute renal failure with potentially life‐threatening metabolic derangements may ensue.
Jason Warren
exaly +4 more sources
AbstractRhabdomyolysis, a syndrome of skeletal muscle breakdown with leakage of muscle contents, is frequently accompanied by myoglobinuria, and if sufficiently severe, acute renal failure with potentially life‐threatening metabolic derangements may ensue.
Jason Warren
exaly +4 more sources
Nursing, 2007
Rhabdomyolysis is a syndrome involving the breakdown of skeletal muscle causing myoglobin and other intracellular proteins and electrolytes to leak into the circulation. The development of rhabdomyolysis is associated with a wide variety of diseases, injuries, medications and toxins.
Terri, Kress +2 more
+7 more sources
Rhabdomyolysis is a syndrome involving the breakdown of skeletal muscle causing myoglobin and other intracellular proteins and electrolytes to leak into the circulation. The development of rhabdomyolysis is associated with a wide variety of diseases, injuries, medications and toxins.
Terri, Kress +2 more
+7 more sources
Orthopaedic Nursing, 2005
Rhabdomyolysis is the dissolution of skeletal muscle. Breakdown of the myocyte causes the extravasation of intracellular constituents, leading to a clinical syndrome--the classic triad of brown urine, muscle pain, and weakness. The pathogenesis of rhabdomyolysis is presented.
D, Singh, V, Chander, K, Chopra
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Rhabdomyolysis is the dissolution of skeletal muscle. Breakdown of the myocyte causes the extravasation of intracellular constituents, leading to a clinical syndrome--the classic triad of brown urine, muscle pain, and weakness. The pathogenesis of rhabdomyolysis is presented.
D, Singh, V, Chander, K, Chopra
openaire +4 more sources
[Rhabdomyolysis: role of the nephrologist].
Rhabdomyolysis is characterized by skeletal muscle necrosis resulting in release of large amounts of toxic muscle cell components, including electrolytes, myoglobin, and other sarcoplasmic proteins into circulation. Creatinine phosphokinase (CPK) and myoglobin serum levels constitute the diagnostic hallmark.
FORCELLINI, Silvia +3 more
core +6 more sources
Critical Care Clinics, 1999
Dissolution of the skeletal muscle, resulting in extravasation of the intracellular toxic metabolites into the circulatory system, and the accompanying manifestations, constitutes the clinical syndrome of rhabdomyolysis. The most frequent complication of this syndrome is acute renal failure, and its most life threatening side effects are hyperkalemia ...
P, Visweswaran, J, Guntupalli
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Dissolution of the skeletal muscle, resulting in extravasation of the intracellular toxic metabolites into the circulatory system, and the accompanying manifestations, constitutes the clinical syndrome of rhabdomyolysis. The most frequent complication of this syndrome is acute renal failure, and its most life threatening side effects are hyperkalemia ...
P, Visweswaran, J, Guntupalli
openaire +2 more sources

