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Recent advances in our understanding of genetic rhabdomyolysis
Current Opinion in Neurology, 2022Purpose of review This review summarizes recent advances in our understanding of the genetics of rhabdomyolysis. Recent findings Rhabdomyolysis is the acute breakdown of myofibres resulting in systemic changes that can be life-threatening.
M. Cabrera-Serrano, G. Ravenscroft
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Rhabdomyolysis and Acute Kidney Injury
New England Journal of Medicine, 2009Xavier Bosch
exaly +2 more sources
Critical Care Clinics, 1999
Dissolution of the skeletal muscle, resulting in extravasation of the intracellular toxic metabolites into the circulatory system, and the accompanying manifestations, constitutes the clinical syndrome of rhabdomyolysis. The most frequent complication of this syndrome is acute renal failure, and its most life threatening side effects are hyperkalemia ...
P, Visweswaran, J, Guntupalli
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Dissolution of the skeletal muscle, resulting in extravasation of the intracellular toxic metabolites into the circulatory system, and the accompanying manifestations, constitutes the clinical syndrome of rhabdomyolysis. The most frequent complication of this syndrome is acute renal failure, and its most life threatening side effects are hyperkalemia ...
P, Visweswaran, J, Guntupalli
openaire +2 more sources
American Journal of Surgery, 2021
BACKGROUND The treatment of rhabdomyolysis remains controversial. Although there is no question that any associated compartment syndrome needs to be identified and released, debate persists regarding the benefit of further therapy including aggressive ...
J. Sawhney +7 more
semanticscholar +1 more source
BACKGROUND The treatment of rhabdomyolysis remains controversial. Although there is no question that any associated compartment syndrome needs to be identified and released, debate persists regarding the benefit of further therapy including aggressive ...
J. Sawhney +7 more
semanticscholar +1 more source
The FASEB Journal, 2019
Acute kidney injury is a common complication of rhabdomyolysis. A better understanding of this syndrome may be useful to identify novel therapeutic targets because there is no specific treatment so far.
Melania Guerrero-Hue +14 more
semanticscholar +1 more source
Acute kidney injury is a common complication of rhabdomyolysis. A better understanding of this syndrome may be useful to identify novel therapeutic targets because there is no specific treatment so far.
Melania Guerrero-Hue +14 more
semanticscholar +1 more source
Rhabdomyolysis: A syndrome to be considered.
Medicina clínica (Ed. impresa), 2021Rhabdomyolysis is characterized by the release of intracellular elements after the destruction of skeletal muscle. Is characterized by the presence of muscle pain, weakness, and dark urine, associated with elevated creatine kinase (CK).
R. Baeza-Trinidad
semanticscholar +1 more source
Southern Medical Journal, 2008
Virus-induced myopathy can be an important cause of life-threatening rhabdomyolysis. We report the case of a 30-year-old patient who developed rhabdomyolysis and acute renal failure in association with herpes simplex virus infection.
Sucharitha, Shanmugam +1 more
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Virus-induced myopathy can be an important cause of life-threatening rhabdomyolysis. We report the case of a 30-year-old patient who developed rhabdomyolysis and acute renal failure in association with herpes simplex virus infection.
Sucharitha, Shanmugam +1 more
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Archives of Academic Emergency Medicine, 2021
Introduction: Determining the diagnostic value of available biomarkers in predicting rhabdomyolysis-induced acute kidney injury (AKI) is a priority. This study aimed to review the current evidence about the value of lactate dehydrogenase (LDH) in this ...
Hazhir Heidari Beigvand +3 more
semanticscholar +1 more source
Introduction: Determining the diagnostic value of available biomarkers in predicting rhabdomyolysis-induced acute kidney injury (AKI) is a priority. This study aimed to review the current evidence about the value of lactate dehydrogenase (LDH) in this ...
Hazhir Heidari Beigvand +3 more
semanticscholar +1 more source
Current pharmaceutical design, 2021
Variants in the ryanodine receptor-1 gene (RYR1) have been associated with a wide range of neuromuscular conditions, including various congenital myopathies and malignant hyperthermia (MH).
N. Kruijt +8 more
semanticscholar +1 more source
Variants in the ryanodine receptor-1 gene (RYR1) have been associated with a wide range of neuromuscular conditions, including various congenital myopathies and malignant hyperthermia (MH).
N. Kruijt +8 more
semanticscholar +1 more source
Journal of Paediatrics and Child Health, 2000
Abstract: Although rhabdomyolysis is an uncommon disorder, especially in children, it can present as a severe, life‐threatening event. Paediatricians need to be aware of this important, probably underdiagnosed disorder in order to implement appropriate early treatment.
Y T, Ng, H M, Johnston
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Abstract: Although rhabdomyolysis is an uncommon disorder, especially in children, it can present as a severe, life‐threatening event. Paediatricians need to be aware of this important, probably underdiagnosed disorder in order to implement appropriate early treatment.
Y T, Ng, H M, Johnston
openaire +2 more sources