Results 101 to 110 of about 67,402 (252)

Relationship Between PTBP1 and Pancreatic Cancer Based on microRNA and Behavior During TYMS‐Mediated Carcinogenesis

Cancer Science, EarlyView.
Corresponding Author and colleagues identify a pancreas‐enriched microRNA, miR‐216b‐5p, that suppresses PTBP1 and its downstream effector TYMS. Their findings reveal a novel miR‐216b‐5p/PTBP1/TYMS regulatory axis driving pancreatic cancer progression and establish PTBP1 as a central molecular regulator of tumor biology beyond its metabolic role ...
Shigenori Suzuki, Hiroaki Hase, Yosuke Inomata, Jun Arima, Kentaro Jingushi, Atsushi Tomioka, Nao Kawaguchi, Hiroki Hamamoto, Ryo Tanaka, Yoshiro Imai, Mitsuhiro Asakuma, Tomohito Tanaka, Kazutake Tsujikawa, Kohei Taniguchi, Sang‐Woong Lee   +14 more
wiley   +1 more source

Integrative Bayesian Analysis Identifies Rhabdomyosarcoma Disease Genes

Cell Reports, 2018
Summary: Identifying oncogenic drivers and tumor suppressors remains a challenge in many forms of cancer, including rhabdomyosarcoma. Anticipating gene expression alterations resulting from DNA copy-number variants to be particularly important, we ...
Lin Xu, Yanbin Zheng, Jing Liu, Dinesh Rakheja, Sydney Singleterry, Theodore W. Laetsch, Jack F. Shern, Javed Khan, Timothy J. Triche, Douglas S. Hawkins, James F. Amatruda, Stephen X. Skapek   +11 more
doaj   +1 more source

Malignant phyllodes tumors display mesenchymal stem cell features and aldehyde dehydrogenase/disialoganglioside identify their tumor stem cells. [PDF]

, 2014
IntroductionAlthough breast phyllodes tumors are rare, there is no effective therapy other than surgery. Little is known about their tumor biology.
Chou, Fen-Pi, Huang, Chiun-Sheng, Hung, Jung-Tung, Liao, Guo-Shiou, Lien, Huang-Chun, Lin, Jin-Jin, Lin, Ruey-Jen, Yeh, Kun-Tu, Yu, Alice L, Yu, John   +9 more
core   +3 more sources

Eccrine Squamous Syringometaplasia Mimicking Acute Cutaneous GVHD in a Pediatric HSCT Recipient: Case Report and Brief Review of the Indexed Literature

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Eccrine squamous syringometaplasia (ESS) is an uncommon reactive alteration of eccrine ducts, most often reported in oncologic and transplant settings, where it may clinically mimic acute cutaneous graft‐versus‐host disease (GVHD). We describe a 3‐year‐old boy with chronic granulomatous disease who developed a diffuse erythematous eruption 6 ...
Benedetta Galli, Cecilia Catapano, Iacopo Ghini, Mariateresa Rossi, Marina Venturini, Valeria Boccaletti   +5 more
wiley   +1 more source

Viruses disrupt functions of human lymphocytes. Effects of measles virus and influenza virus on lymphocyte-mediated killing and antibody production. [PDF]

, 1984
We present experimental data that offer, in part, a better understanding of the immunosuppression that accompanies measles virus infection. We note that measles virus "silently" infects human lymphocytes and that the infection does not alter lymphocyte ...
Casali, P, Oldstone, MB, Rice, GP
core  

Temozolomide combined with irinotecan caused regression in an adult pleomorphic rhabdomyosarcoma patient-derived orthotopic xenograft (PDOX) nude-mouse model. [PDF]

, 2017
Adult pleomorphic rhabdomyosarcoma (RMS) is a rare and recalcitrant, highly-malignant mesenchymal tumor in need of improved therapeutic strategies.
Dry, Sarah M, Eilber, Fritz C, Hayashi, Katsuhiro, Hoffman, Robert M, Igarashi, Kentaro, Kawaguchi, Kei, Kimura, Hiroaki, Kiyuna, Tasuku, Li, Yunfeng, Miwa, Shinji, Murakami, Takashi, Nelson, Scott D, Singh, Arun S, Tsuchiya, Hiroyuki, Yamamoto, Norio   +14 more
core   +1 more source

Nasopharyngeal rhabdomyosarcoma

Indian Journal of Otolaryngology and Head and Neck Surgery, 2000
Nasopharyngeal Rhabdomyosarcama, a common soft tissue sarcoma in children, is a rare identity, only four cases so far have been reported as per the review of literature. Ours is the fifth case presented exclusively in the nasopharynx, which is reported, hereby.
K K, Desarda, S J, Gill, M P, Bora
openaire   +3 more sources

Emerging Techniques in Minimally Invasive Surgery in Hematologic Malignancies

European Journal of Haematology, EarlyView.
ABSTRACT Hematologic malignancies represent the most common cancers in children. While the mainstays of treatment are chemotherapy and potentially hematopoietic stem cell transplant, minimally invasive surgery (MIS) has a role in the diagnosis and management of complications related both to disease and therapy as well as common pediatric surgical ...
Alejandro Chara, Katlyn G. McKay, Harold N. Lovvorn III, Joseph C. Fusco   +3 more
wiley   +1 more source

Costello Syndrome and Umbilical Ligament Rhabdomyosarcoma in Two Pediatric Patients: Case Reports and Review of the Literature

Case Reports in Genetics, 2017
Costello syndrome is caused by heterozygous de novo missense mutations in the protooncogene HRAS with tumor predisposition, especially rhabdomyosarcoma. We here report two pediatric patients with Costello syndrome and umbilical ligament rhabdomyosarcoma.
Carlos Sánchez-Montenegro, Alejandra Vilanova-Sánchez, Saturnino Barrena-Delfa, Jair Tenorio, Fernando Santos-Simarro, Sixto García-Miñaur, Pablo Lapunzina, Leopoldo Martínez-Martínez   +7 more
doaj   +1 more source

PARP inhibitors affect growth, survival and radiation susceptibility of human alveolar and embryonal rhabdomyosarcoma cell lines [PDF]

, 2018
PARP inhibitors (PARPi) are used in a wide range of human solid tumours but a limited evidence is reported in rhabdomyosarcoma (RMS), the most frequent childhood soft-tissue sarcoma.
Camero, S, Camicia, L, Ceccarelli, S, De Felice, F, Dominici, C, Mannarino, O, Marampon,, Marchese, C, Megiorni, F, Mollace, Mg, Pizer, B, Pizzuti, Antonio, Pontecorvi, P, Schiavetti, A, Shukla, R, Tombolini, V, Vescarelli, E   +16 more
core   +1 more source