Results 71 to 80 of about 3,058 (211)
Microbiology Spectrum, 2023 Myxoma virus (MYXV) and rabbit hemorrhagic disease virus (RHDV) are important drivers of the population decline of the European rabbit, an endangered keystone species.
Joana Coelho +5 more
doaj +1 more source
Medicinal Research Reviews, Volume 45, Issue 6, Page 1850-1882, November 2025.ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro +5 more
wiley +1 more source
Microbiology Spectrum, 2022 Lagovirus europaeus (rabbit hemorrhagic disease virus [RHDV]) is a small, nonenveloped, single-stranded RNA virus that causes a severe, highly infectious, and fatal disease in rabbits (Oryctolagus cuniculus) called rabbit hemorrhagic disease (RHD). Since
Rafał Hrynkiewicz +5 more
doaj +1 more source
Advancing ORFV‐Based Therapeutics to the Clinical Stage
Reviews in Medical Virology, Volume 35, Issue 3, May 2025.ABSTRACT The Orf virus (ORFV) is the prototype member of the parapoxvirus family and has long been recognized for its robust immunogenicity, favourable safety profile and its ability to stimulate both cellular and humoural immune responses without inducing significant anti‐vector immunity.
Matthias Helmold, Ralf Amann
wiley +1 more source
Genogroup IV and VI canine noroviruses interact with histo-blood group antigens. [PDF]
, 2014 UNLABELLED: Human noroviruses (HuNV) are a significant cause of viral gastroenteritis in humans worldwide. HuNV attaches to cell surface carbohydrate structures known as histo-blood group antigens (HBGAs) prior to internalization, and HBGA polymorphism ...
Breiman, Adrien +3 more
core +8 more sources
Advancing the field of viroporins—Structure, function and pharmacology: IUPHAR Review 39
British Journal of Pharmacology, Volume 181, Issue 22, Page 4450-4490, November 2024.Viroporins possess important potential as antiviral targets due to their critical roles during virus life cycles, spanning from virus entry to egress. Although the antiviral amantadine targets the M2 viroporin of influenza A virus, successful progression of other viroporin inhibitors into clinical use remains challenging.
Kira Devantier +4 more
wiley +1 more source
In silico screening for human norovirus antivirals reveals a novel non-nucleoside inhibitor of the viral polymerase [PDF]
, 2018 Human norovirus causes approximately 219,000 deaths annually, yet there are currently no antivirals available. A virtual screening of commercially available drug-like compounds (~300,000) was performed on the suramin and PPNDS binding-sites of the ...
Ferla, Salvatore +8 more
core +3 more sources
RNA-Dependent RNA Polymerases of Both Virulent and Benign Rabbit Caliciviruses Induce Striking Rearrangement of Golgi Membranes. [PDF]
PLoS ONE, 2017 The extremely pathogenic Rabbit haemorrhagic disease virus (RHDV) and the completely benign Rabbit calicivirus (RCV) are closely related members of the genus Lagovirus (family Caliciviridae).
Nadya Urakova +2 more
doaj +1 more source
Ecosphere, Volume 15, Issue 9, September 2024.Abstract Infectious diseases can cause considerable mortality in vertebrate populations, especially when a new pathogen emerges. Quantifying the impact of diseases on wild populations and dissecting the underlying mechanisms requires longitudinal individual monitoring combining demographic and epidemiologic data.
Jérôme Letty +7 more
wiley +1 more source
Detection of a new variant of rabbit haemorrhagic disease virus in wild rabbits in Spain [PDF]
, 2012 El virus de la enfermedad hemorrágica del conejo (RHDV) suele causar elevadas mortalidades tanto en conejos domésticos como en silvestres. Hasta el momento actual, todas las variantes víricas detectadas en la Península Ibérica proceden de un único ...
Calvete Margolles, Carlos +2 more
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