Results 191 to 200 of about 126,869 (297)

Mechanistic insights into the multi-target anti-atherosclerotic actions of rhubarb: a traditional remedy revisited. [PDF]

Chin Med
Hu FJ, Tang YM, Hu BY, Yang FN, Jin W, Miao YF, Lu Y.   +6 more
europepmc   +1 more source

Effects of Vicadrostat/Empagliflozin in People With Chronic Kidney Disease: Metabolic Subgroup Analyses

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims In a phase 2 trial, the efficacy and safety of the highly selective aldosterone synthase inhibitor vicadrostat, alone or with empagliflozin, were investigated in people with chronic kidney disease (CKD) with or without type 2 diabetes (T2D). Materials and Methods Adults (n = 586) with CKD (estimated glomerular filtration rate [eGFR] 30 to
David Z. I. Cherney, Peter Rossing, Maria Eugenia Canziani, Maria Luiza Caramori, Ricardo Correa‐Rotter, Lisa Cronin, Christian Hugo, Bo Ji, Juliane Meyerhoff, Masaomi Nangaku, Arnold Silva, Dorothea Urbach, Shimoli V. Shah, Dick de Zeeuw, Katherine R. Tuttle   +14 more
wiley   +1 more source

Rhein alleviates renal interstitial fibrosis by inhibiting Smad3 phosphorylation in TGF-<i>β</i>/Smad signalling pathway. [PDF]

Chin Herb Med
Zheng X, Wang L, Cheng Y, Lin H, Liu S, Chen X, Xiang Z.   +6 more
europepmc   +1 more source

Natural Parasitism of Nezara viridula (Linnaeus) (Hemiptera: Pentatomidae) by Trichopoda pictipennis Bigot (Diptera: Tachinidae) in an Organic Strawberry Field in Germany

Entomologia Experimentalis et Applicata, EarlyView.
Natural parasitism of the invasive southern green stinkbug was recorded in an organic strawberry cropping system in southwestern Germany. The tachinid fly Trichopoda pictipennis shows successful establishment and field activity, indicating ongoing range expansion.
Sophie Wenz, Olaf Zimmermann, Annette Reineke   +2 more
wiley   +1 more source

Editorial: COVID-19 - lessons learned in pediatrics. [PDF]

Front Pediatr
von Rhein M, Dratva J, Seiler M.
europepmc   +1 more source

The slow emergence of the rational investor: Grain markets and grain storage of rural estates in western Germany, eighteenth and early nineteenth centuries

The Economic History Review, EarlyView.
Abstract We develop new datasets of monthly grain prices in 14 urban markets and of the storage and marketing of grain by 5 rural estates located in western Germany between the late seventeenth century and c. 1860. We explore whether observed patterns of monthly prices, sales, and storage of grain are consistent with the rational competitive storage ...
Matthias Hartermann, Ulrich Pfister, Friederike Scholten‐Buschhoff   +2 more
wiley   +1 more source

Self-assembly of plant-derived bioactive nanostructures in traditional Chinese medicine. [PDF]

iScience
Zhu H, Liu M, Wang Z, Mao T, Wu Y, Wei Z, Li X, Lu Y.   +7 more
europepmc   +1 more source

Resistance‐exercise‐induced stress intervenes in TGF‐β signaling by cooperatively downregulating nuclear αB‐crystallin and SMAD4 in human skeletal muscle fibers

The FEBS Journal, EarlyView.
Alpha‐crystallin B chain (CRYAB) has been reported to stabilize mothers against decapentaplegic homolog 4 (SMAD4) in transforming growth factor‐β (TGF‐β) signaling, enabling target gene transcription. We show nuclear CRYAB–SMAD4 interaction for the first time in human skeletal muscle fibers and its regulation by exercise.
Kirill Schaaf, Cassandra Duda, Tihomir Kostov, Patrick Diel, Käthe Bersiner, Wilhelm Bloch, Sebastian Gehlert, Daniel Jacko   +7 more
wiley   +1 more source

Rhubarb: Traditional Uses, Phytochemistry, Multiomics-Based Novel Pharmacological and Toxicological Mechanisms. [PDF]

Drug Des Devel Ther
Miao H, Wang KE, Li P, Zhao YY.
europepmc   +1 more source

Contrasting Approaches in the Implementation of GRADE Methodology in Guidelines for Haemophilia and Von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Introduction The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF‐McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology.
Mark W. Skinner, Manuela Albisetti, Jesús Ardila, Jan Astermark, Jan Blatny, Manuel Carcao, Pratima Chowdary, Nathan T. Connell, Miguel Crato, Yesim Dargaud, Roseline d'Oiron, Amy L. Dunn, Miguel A. Escobar, Carmen Escuriola‐Ettingshausen, Emna Gouider, Annie Harroche, Cedric Hermans, Victor Jimenez‐Yuste, Radoslaw Kaczmarek, Gili Kenet, Liane Khoo, Robert Klamroth, Florian Langer, David Lillicrap, Johnny Mahlangu, Christoph Male, Tadashi Matsushita, Sandrine Meunier, Wolfgang Miesbach, Beatrice Nolan, Johannes Oldenburg, Brian O'Mahony, Margareth Ozelo, Glenn F. Pierce, Gloria Ramos, Michael Recht, Olivia Romero‐Lux, Dawn Rotellini, Rita C. Santoro, Tammuella C. Singleton, Alok Srivastava, Sophie Susen, Kate Talks, Huyen Tran, Leonard A. Valentino, Jerzy Windyga, Renchi Yang, Maria Elisa Mancuso, also on behalf of AICE, AHAD‐AP, AHCDC, ATHN, CLAHT, EHC, French CRH & MHEMO, HTCCNC, NBDF, PEDNET, UKHCDO, WFH   +59 more
wiley   +1 more source