Results 151 to 160 of about 22,580 (293)

Reactions of Terminal Olefins With Iron Carbenes

Angewandte Chemie, EarlyView.
Iron carbenes react with terminal olefins and show productive metathesis or metathesis‐divergent pathways depending on the nature of the olefin. Reactions proceed through 2π + 2π cycloadditions to generate transient metallacyclobutane intermediates that undergo cycloreversion to generate the metathesis product or the metathesis‐divergent β‐hydride ...
Zachary S. Lincoln, Melissa R. Hoffbauer, Vlad M. Iluc   +2 more
wiley   +2 more sources

Unraveling A4GALT Mechanism and Its Modulation With Adamantyl‐Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies

Angewandte Chemie, EarlyView.
A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster, Òscar Vidal‐Gironès, Rowan de Graaf, Ken Kok, Lindsey T. Lelieveld, Jackelien Hoogervorst, Maria J. Ferraz, José Pablo Rivas‐Fernández, Rob F. Lammers, Herman S. Overkleeft, Johannes M. F. G. Aerts, Rolf G. Boot, Carme Rovira, Marta Artola   +13 more
wiley   +2 more sources

Synthesis, Characterisation and Structural Analysis of Rhenium and Technetium Nitride Complexes With Tridentate Thiosemicarbazone-Phenols and Phosphine Ligands: Potential Applications in Technetium-99m Radiotracer Development. [PDF]

Bioinorg Chem Appl
Salvarese N, Lucchini D, Gobbi C, Baron M, Rogolino D, Carcelli M, Dolmella A, Bolzati C.   +7 more
europepmc   +1 more source

Inflammatory Signatures Beyond Th1/Th2 Endotypes Provide Insights Into Postoperative Recurrence in Chronic Rhinosinusitis

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) represents a spectrum of inflammatory endotypes, driven by distinct T helper (Th) immune responses. The high rate of recurrent disease despite appropriate medical and surgical interventions highlights the need for improved characterization beyond the traditional type 2 and non‐type 2 phenotypes to better
Liyona Kampel, Narin N. Carmel, Shaun Edalati, Hen Chaushu, Forsan Jahshan, Yaniv Hadi, Timur Pestrikov, Leonor Leider Trejo, Nidal Muhanna, Avraham Abergel   +9 more
wiley   +1 more source

Chelator Free Radiolabeling and Preclinical Evaluation of η⁶-Arene Sandwich Complexes of Lenalidomide With Rhenium and Technetium-99m. [PDF]

Chembiochem
Nadeem Q, Battistin F, Valdés DH, Genady AR, Mendez LRS, Sadeghi S, Blacque O, Alberto R.   +7 more
europepmc   +1 more source

Safety and Feasibility of Magnetic Separation‐Based Blood Purification

Advanced NanoBiomed Research, EarlyView.
We present the preclinical biological safety and translational feasibility of a magnetic nanoparticle‐based extracorporeal blood purification platform for removal of disease‐causing blood factors. ISO 10993‐compliant studies and exaggerated worst‐case exposure models demonstrate efficient nanoparticle extraction (≥99.9%), favorable biocompatibility ...
Carlos A. Mora, Laurine Rijsbergen, Jan Waskowski, Gaelle Clermont, Florian Dingreville, Chandrashekara Vishwanath, Rajesh Karunanithi, Alexander Gogos, Jean‐Claude Metzger, Manuel Baumgartner, Joerg C. Schefold, Inge K. Herrmann   +11 more
wiley   +1 more source

Understanding the Photodynamic Behavior of Red Emitting Re(I)dipyrrinates in Triple-Negative Breast Cancer Cells. [PDF]

ACS Med Chem Lett
Manav N, Chavda J, Bhatia D, Gupta I.
europepmc   +1 more source

Aktivierung von Metallkomplexen durch Ultraschallwellen für eine gezielte Krebstherapie

Angewandte Chemie, EarlyView.
Ultrasound enables non‐invasive activation of metal‐based therapeutics deep within tumors. Acoustic cavitation can drive sonodynamic reactive oxygen species generation or mechanochemical metal–ligand bond dissociation, enabling controlled release of bioactive payloads.
Félix Grosjean, Nicolás Montesdeoca, Gilles Berger, Johannes Karges   +3 more
wiley   +1 more source

Rhenium-Doped Antimony Trioxide for Biomass Sucrose Upcycling to Generate Formic Acid Coupling Hydrogen Evolution. [PDF]

Chempluschem
Xiong J, Li Y, Yang J, Li M, Dong S, Yang Z.   +5 more
europepmc   +1 more source

Nitrido and Oxo Complexes of Rhenium(V)

, 1992
This chapter contains sections titled: Dichloronirtridobis(triphenylphosphine)rhenium(V),RenCl_2(PPh_3)_2; trans‐Ethyxodiiodooxobis(triphenylphosphine)rhenium(V),ReOl_2(OEt)(PPh_3)_2; Iododioxobis(triphenylphospphine)rhenium(V),ReO_2I(PPh_3 ...
Linebarrier, Douglas, Sullivan, B. Patrick, Brewer, John C., Mayer, James M., Gray, Harry B.   +4 more
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