Results 181 to 190 of about 7,325 (251)
Background Methotrexate (MTX) is the first‐line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients don't respond. Low inosine‐triphosphate‐pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated ITPA role and the underlying mechanisms in vitro.
Sofia Sindici Forgiarini +19 more
wiley +1 more source
Rhenium Chalcogenide Clusters Containing <i>para</i>-Substituted Phenylacetylide Ligands: Synthesis, Characterization, and Investigation of Substituent Effects on Spectroscopic and Electrochemical Properties. [PDF]
Helmink KL +6 more
europepmc +1 more source
Multi‐omic profiling reveals immune cell priming signature linked to lupus prognosis
Objective Systemic lupus erythematosus (SLE) is a multi‐organ disease with widespread immune dysregulation and significant unmet clinical need. Blood‐based gene expression studies have advanced our understanding of SLE pathogenesis but may overlook critical tissue‐specific mechanisms that drive disease heterogeneity and progression.
Michael A. Smith +23 more
wiley +1 more source
A Micro-Nodal Tungsten-Rhenium Thin-Film Thermocouple Based on Electrohydrodynamic Printing. [PDF]
Hu S +9 more
europepmc +1 more source
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/Fn14 signaling in SLE‐related cardiomyopathy and its potential as a ...
Yale Liu +12 more
wiley +1 more source
Synthesis of a <i>fac</i>-Tricarbonylrhenium(I) Complex with Pyrithione, Its Physicochemical Characterization, and Assessment of Biological Effects. [PDF]
Rapuš U +10 more
europepmc +1 more source
Objective Rituximab, a CD20+ B cell depletion therapy, is frequently used to treat systemic lupus erythematosus (SLE). However, variability in patient response highlights the need for a deeper understanding of the underlying immune cell dynamics of B cell depletion and repopulation.
Haerin Jang +9 more
wiley +1 more source
Pinene-Based Chiral Bipyridine Ligands Drive Potent Antibacterial Activity in Rhenium(I) Complexes. [PDF]
Horner J +5 more
europepmc +1 more source
Special Issue "Metal Nanoparticles: From Fundamental Studies to New Applications". [PDF]
Konował E, Modrzejewska-Sikorska A.
europepmc +1 more source

