Results 211 to 220 of about 19,547 (300)

Boosting Antibiotic Efficacy of Azole Drugs against Methicillin-Resistant Staphylococcus Aureus by Coordination to Rhenium Carbonyl Complexes. [PDF]

open access: yesChembiochem
Schindler K   +12 more
europepmc   +1 more source

Dilithium Enediamide Derived From a 1,4‐Diaza‐1,3‐diene: Reactivity of a Strongly N‐Basic, Highly C‐Nucleophilic Compound Toward C–H Acids

open access: yesEuropean Journal of Inorganic Chemistry, EarlyView.
The lithium enediamide complex 2 with intrinsically inverted C–N bond polarity combines strong basicity with unusual reactivity: deprotonation of malonates enables C–C bond formation without electron transfer. Depending on malonate substitution, electrophilic substitution or addition occurs at the enediamide CC bond.
Muhan Liang   +3 more
wiley   +1 more source

Dilithium Enediamide Derived From 1,4‐Diaza‐1,3‐Diene: An Electron Reservoir Enabling Variable Reactivity Toward Carbonyl Compounds

open access: yesEuropean Journal of Inorganic Chemistry, EarlyView.
Upon reduction of 1,4‐diaza‐1,3‐diene 1 to the dilithium enediamide 2, the polarity of the C = N bonds is reversed ‐ a classic case of umpolung. This behavior is particularly evident in reactions of the dianion 2 with carbonyl compounds and also explains why 1,4‐diaza‐1,3‐diene ligands do not always act merely as spectator ligands. 1,4‐Diaza‐1,3‐dienes
Muhan Liang   +3 more
wiley   +1 more source

Lipid‐based Nano‐delivery systems as a promising strategy for the treatment of epilepsy: Current status and challenges

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini   +9 more
wiley   +1 more source

Evaluation of the Adequacy of Design Specifications for Nonstructural Components in a Reticular Structure

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Nonstructural components (NSCs) installed in large‐span reticular structures were frequently severely damaged during earthquakes, even when the primary structure remained intact. Existing seismic design specifications for NSCs were predominantly developed for upright structures such as multi‐storey buildings and offer no guidance for reticular
Xudong Zhi   +6 more
wiley   +1 more source

Quinoline and coumarin isoxazole derivatives: synthesis, antitumor evaluation and molecular docking studies with Bcl-2. [PDF]

open access: yesRSC Adv
Piškor M   +8 more
europepmc   +1 more source

An Efficient Quasi‐Static Condensation‐Based Framework for Seismic Analysis of Multi‐Supported Secondary Structures

open access: yesEarthquake Engineering &Structural Dynamics, EarlyView.
ABSTRACT Multi‐supported non‐structural components (NSCs) are prone to seismic damage, yet their response prediction remains challenging when support motions are spatially incoherent. This study proposes an enhanced quasi‐static condensation (EQSC) method for linear, lightweight, dynamically detuned multi‐supported NSCs under the neglect of primary ...
Duozhi Wang   +5 more
wiley   +1 more source

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