Results 201 to 210 of about 301,408 (296)

Diagnostic utility of the revised Lake Louise criteria in myocarditis associated with active autoimmune rheumatic disease. [PDF]

J Cardiovasc Magn Reson
Hua A, Domenech-Ximenos B, Lopez B, Sanna G, Chiribiri A, Rajani R, Marber M, D'Cruz D, Fernando M, Ismail TF.   +9 more
europepmc   +1 more source

DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss

Advanced Science, EarlyView.
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim, Kridtapat Sirisereephap, Hui Wang, Giulia Trimaglio, Kyoung‐Jin Chung, Jonathan Korostoff, Tetsuhiro Kajikawa, Xiaofei Li, Meircurius D.C. Surboyo, Tomoki Maekawa, Triantafyllos Chavakis, George Hajishengallis   +11 more
wiley   +1 more source

Potentials and barriers of digital patient education in rheumatic disease management: an exploratory qualitative interview study. [PDF]

Rheumatol Int
Lumma F, Knitza J, Mühlensiepen F.
europepmc   +1 more source

TRIM56 Aggravates Cerebral Ischemia‐Reperfusion Injury via Inhibiting KLF4‐Activated Ferroptosis Signaling

Advanced Science, EarlyView.
This study reveals that the E3 ubiquitin ligase TRIM56 exacerbates neuronal ferroptosis and brain damage by mediating K48‐linked ubiquitination and degradation of KLF4, leading to suppression of the xCT/GSH/GPX4 axis. Targeting TRIM56 alleviates cerebral ischemia‐reperfusion injury in vivo and in vitro, highlighting its therapeutic potential.
Qiangping Wang, Shuang Li, Man Li, Wenke Zhou, Jianqing Zhang, Zhenfu Wu, Zhaoqi Mao, Juan Wan, Xinhao Tang, Baoping Zheng, Qiang Liu, Zhendong Li, Xiaobing Jiang, Qingping Wu, Youfan Ye, Haijun Wang   +15 more
wiley   +1 more source

From Awareness to Action: Addressing Knowledge Barriers and Promoting Herpes Zoster Vaccination in Chinese Rheumatic Disease Patients. [PDF]

Vaccines (Basel)
Geng Y, Lu B, Xie W, Wang Y, Deng X, Zhao J, Li G, Zhang X, Song Z, Zhang Z.   +9 more
europepmc   +1 more source

Incidence and Risk of Malignancy in Japanese Patients With Rheumatoid Arthritis in the National Database of Rheumatic Diseases in Japan ( NinJa Database) [PDF]

Toshihiro Matsui, Aosa Kamezaki‐Nakagawa, Masato Hoshi, Hiroshi Hirano, Naonobu Sugiyama, Toshitaka Hirano, Miki Enami, Shigeyuki Toyoizumi, Fujio Matsuyama, Tatsunori Murata, Yukitomo Urata, Kimito Kawahata, Shigeto Tohma   +12 more
openalex   +1 more source

Heat Stress Modulates WDR5‐Mediated H3K4me3 Modification to Induce Melanogenesis via Activating CX3CL1/CX3CR1 Axis

Advanced Science, EarlyView.
This study elucidates the mechanism by which heat stress regulates skin pigmentation: heat stress upregulates CX3CL1 through the MYC‐WDR5‐H3K4me3 axis, thereby activating the CX3CL1/CX3CR1‐JNK signaling pathway and ultimately promoting melanogenesis. These findings provide novel potential therapeutic targets for pigmentary skin disorders.
Yushan Zhang, Ling Jiang, Yibo Hu, Chuhan Fu, Jinhua Huang, Jing Chen, Qinghai Zeng   +6 more
wiley   +1 more source

Utility of unilateral biportal endoscopy in the evacuation of delayed multi-level postoperative symptomatic lumbar epidural hematoma: A case report

Asian Journal of Surgery
Changjun Chen, Qibin Liu, Qingwei Ma, Lei Zhang   +3 more
doaj   +1 more source

Spatial transcriptomics in autoimmune rheumatic disease: potential clinical applications and perspectives. [PDF]

Inflamm Regen
Miyamoto AT, Shimagami H, Kumanogoh A, Nishide M.   +3 more
europepmc   +1 more source

MORTALITY PATTERNS OF RHEUMATIC HEART DISEASE IN CENTRAL AND SOUTH AMERICAN NATIONS

Valerie Wang, Neo Hou
openalex   +1 more source