Results 221 to 230 of about 292,383 (379)

Erythropoietin‐Stimulated Macrophage‐Derived Extracellular Vesicles in Chitosan Hydrogel Rescue BMSCs Fate by Targeting EGFR to Alleviate Inflammatory Bone Loss in Periodontitis

Advanced Science, EarlyView.
A therapeutic strategy is proposed for periodontitis using extracellular vesicles derived from EPO‐stimulated macrophages (EPO‐EVs). This schema demonstrates how EPO‐EVs enhance the osteogenic activity of mBMSCs in an inflammatory environment by inhibiting EGFR.
Shuchen Liu, Zhuoran Wang, Yuhuan Li, Ziyi Pan, Lei Huang, Jing Cui, Xue Zhang, Mingxi Yang, Yuan Zhang, Daowei Li, Hongchen Sun   +10 more
wiley   +1 more source

Prevalence Of Rheumatic Fever and Rheumatic Heart Disease in School Children in Malwa Region Of MP

National Journal of Community Medicine, 2010
Rheumatic fever and rheumatic heart disease continue to affect   millions of people around the world. Children and adolescents of the developing countries are especially susceptible to this disease.
P. Yadav, P. Joshi, J. Gupta, D. Joseph, P. Sakhi   +4 more
doaj  

Medical Disorders of the Locomotor System Including the Rheumatic Diseases.Ernest Fletcher

, 1950
Nephi K. Kezerian
openalex   +1 more source

IL‐33‐Induced TREM2+ Macrophages Promote Pathological New Bone Formation Through CREG1‐IGF2R Axis in Ankylosing Spondylitis

Advanced Science, EarlyView.
This study identifies TREM2+ macrophages as key contributors to pathological bone formation in ankylosing spondylitis (AS). These macrophages mediate pathological new bone formation via the CREG1‐IGF2R‐PI3K‐AKT pathway and are regulated by IL‐33 through STAT6 phosphorylation.
Wenjun Hao, Siwen Chen, Hua Chao, Zihao Li, Hao Yang, Dongying Chen, Sifang Li, Shuai Zhang, Jingyu Zhang, Jianru Wang, Zemin Li, Xiang Li, Zhongping Zhan, Tangming Guan, Yiwen Zhang, Wende Li, Hui Liu   +16 more
wiley   +1 more source

Rheumatic heart disease in identical twins [PDF]

, 1941

openalex   +1 more source

Hypothalamus Regulates Anabolic Metabolism of Articular Cartilage Superficial Chondrocytes through PGE2 Skeletal Interoception

Advanced Science, EarlyView.
Hypothalamus sympathetic norepinephrine inhibits regeneration of articular cartilage. Mechanical loading on bone during animal activity elevates PGE2 skeletal interoception to promote an anabolic renewal of the superficial membrane by downregulation of norepinephrine for articular cartilage proper thickness and integrity.
Ziyi Wang, Xuequan Han, Jiawen Xu, Weixin Zhang, Kalp Patel, Jinjian Zheng, Mei Wan, Junying Zheng, Xu Cao   +8 more
wiley   +1 more source

Discussion on Neurological Aspects of Rheumatic Diseases [PDF]

, 1949

openalex   +1 more source

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen   +11 more
wiley   +1 more source

Digest of morbidity and mortality data on the rheumatic diseases. [PDF]

, 1969

openalex   +1 more source

Bacterial Capture‐Killing Capsules with Remodeling Bone Immune Microenvironment for the Effective Treatment of Osteomyelitis

Advanced Science, EarlyView.
The PC‐O@TOB capsules are designed to exhibit bactericidal effects, regulate the bone immune microenvironment by promoting M2 macrophage polarization, eliminate excessive ROS, and enhance bone regeneration, providing a novel multi‐dimensional approach for the treatment of osteomyelitis.
Dong Yang, Chang Shu, Chengwei Xu, Xingjie Zan, Shaoyin Wei, Chenglong Wang, Lianxin Li   +6 more
wiley   +1 more source