Results 251 to 260 of about 298,218 (361)

Neutrophil Macrophage Crosstalk via Extracellular Vesicles Drives Reverse Migration in a Fully Human Model of Wound Healing

open access: yesAdvanced Science, EarlyView.
A novel microphysiological system that can mimic sterile or non‐sterile injury demonstrates that macrophage‐derived extracellular vesicles modulate neutrophil migratory responses to these different wound states. The model showed that resolution of inflammation through neutrophil reverse migration is driven by IL‐8 derived from extracellular vesicles ...
Kehinde Adebayo Babatunde   +5 more
wiley   +1 more source

The Limitation of HLA Diversity as a Risk Factor for Pediatric-Onset Autoimmune Rheumatic Disease. [PDF]

open access: yesJ Clin Med
Kalampokis I   +6 more
europepmc   +1 more source

Research Progress on Biomaterials with Immunomodulatory Effects in Bone Regeneration

open access: yesAdvanced Science, EarlyView.
This review highlights recent advanced in immunomodulatory biomaterials for bone repair, focusing on design strategies, immune interactions, and clinical potential. Abstract The immune system plays a pivotal role in bone regeneration, and biomaterials engineered to modulate immune responses present a promising strategy for the treatment of extensive ...
Jianan Li   +11 more
wiley   +1 more source

Pinosylvin Inhibits Inflammatory and Osteoclastogenesis via NLRP3 Inflammasome

open access: yesAdvanced Science, EarlyView.
Pinosylvin blocks LPS and RANKL induced NEK7/NLRP3 interaction, inhibiting NLRP3 inflammasome oligomerization and assembly, reducing IL‐1β maturation and GSDMD cleavage, and improving the inflammatory microenvironment and abnormal osteoclastogenesis. Abstract Pro‐inflammatory cytokines such as TNF, IL‐1, and IL‐6 trigger aberrant osteoclastogenesis and
Wei Zhang   +13 more
wiley   +1 more source

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