Results 291 to 300 of about 298,218 (361)

Differences in Salivary Cytokinome and Pathogen Load Between Rheumatoid Arthritis and Other Rheumatic Disease Patients. [PDF]

Int J Mol Sci
Korzeniowska A, Daca A, Szarecka M, Bykowska M, Witkowski J, Bryl E.   +5 more
europepmc   +1 more source

Targeting eRNA‐Producing Super‐Enhancers Regulates TNFα Expression and Mitigates Chronic Inflammation in Mice and Patient‐Derived Immune Cells

Advanced Science, EarlyView.
Targeting eRNAs from TNFα‐associated super‐enhancers with ASOs effectively reduces TNFα expression and inflammatory responses in both mouse models and patient‐derived immune cells. The conserved nature of these regulatory regions between species highlights the potential of eRNA‐targeted approaches as a therapeutic strategy for chronic inflammatory ...
Minjeong Cho, Su Min Kim, Jiyeon Lee, Oh Chan Kwon, Wonjin Woo, Eunji Lee, Hyo Jin Park, Yeongun Lee, So Hee Dho, Tae‐Kyung Kim, Min‐Chan Park, Richard A. Flavell, Lark Kyun Kim   +12 more
wiley   +1 more source

Experiences of sexual and reproductive health screening and counseling in the clinical setting among adolescents and young adults with rheumatic disease. [PDF]

Pediatr Rheumatol Online J
Huynh B, Ott MA, Tarvin SE.
europepmc   +1 more source

Advances in Medical Devices for Augmented Acupuncture Therapy

Advanced Science, EarlyView.
Traditional acupuncture therapy faces several challenges in clinical applications, such as complex operation procedures and prolonged therapeutic periods. By incorporating physical stimulations and drug delivery technologies, engineered acupuncture needles (EANs) can enhance therapeutic efficacy, improve patient compliance, as well as mitigate ...
Ruisi Cai, Chenyi Yu, Xinyi Luo, Ningyu Xu, Jicheng Yu, Xiao Ye, Yuqi Zhang, Zhen Gu   +7 more
wiley   +1 more source

MIP-C: A new autoimmune rheumatic disease concomitant with the COVID-19 pandemic. [PDF]

Rheumatol Immunol Res
Brion K, Phillips M, La Cava A.
europepmc   +1 more source

Inhalable Artificial Polymeric Nucleases Degrading Neutrophil Extracellular Trap‐DNAs and Alleviating Pulmonary Fibrosis

Advanced Science, EarlyView.
Pulmonary fibrosis (PF) is promoted by NETs that induce fibroblast activation. PEG‐PIm, a polymeric artificial DNase is reported that efficiently degrades NET‐DNA via phosphodiester bond hydrolysis. Inhalation of PEG‐PIm in a mouse PF model prevents fibroblast activation and fibrosis progression, offering a promising therapeutic strategy for NET ...
Yibo Du, Chenxu Zhu, Ruifeng Wang, Shi Chen, Chuang Li, Defang OuYang, Lixin Liu, Yongming Chen   +7 more
wiley   +1 more source

High risk of misclassification of acute Parvovirus B19 infection into a systemic rheumatic disease. [PDF]

Rheumatol Adv Pract
D'Onofrio B, Virelli G, Pedrollo E, Caprioli M, Riva M, Renna D, Tonutti A, Luciano N, Ceribelli A, Gremese E, De Santis M, Selmi C.   +11 more
europepmc   +1 more source

Health at Older Ages: The Causes and Consequences of Declining Disability among the Elderly [PDF]

Dora L. Costa
core  

Megasphaera Elesdenii Dysregulates Colon Epithelial Homeostasis, Aggravates Colitis‐Associated Tumorigenesis

Advanced Science, EarlyView.
A fecal microbial meta‐analysis reveals that Megasphaera is highly abundant in the Asian population with IBD and CRC. M. elsdenii reshapes colonic immunity by triggering DC cell‐mediated Th1 and Th17 inflammation. M. elsdenii and M. elsdenii‐enriched microbiota exacerbate colonic inflammation and tumorigenesis in AOM/DSS mice.
Xinxin Hou, Zhaozhou Zhang, Wanqing Chen, Jinming Li, Xiangxiang Zhu, Mingjie Li, Xiaoqi Guan, Haidong Guo, Yanlei Ma, Ling Zhao   +9 more
wiley   +1 more source

Emerging Role and Mechanism of Mesenchymal Stem Cells-Derived Extracellular Vesicles in Rheumatic Disease. [PDF]

J Inflamm Res
Wang Z, Yang C, Yan S, Sun J, Zhang J, Qu Z, Sun W, Zang J, Xu D.   +8 more
europepmc   +1 more source