Chronic systemic inflammation, worsened by estrogen deficiency, underlies and exacerbates periodontitis. Proinflammatory macrophages within visceral adipose tissue are hyperactivated due to hyper‐DNA methylation, releasing small extracellular vesicles (sEVs) similar to those of their parent cells.
Danfeng Li+6 more
wiley +1 more source
Interpreting and Addressing Racialized Inequities in Rheumatic Disease Care and Outcomes. [PDF]
Yang S, Feldman CH.
europepmc +1 more source
Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan+10 more
wiley +1 more source
Association between infertility and incident onset of systemic autoimmune rheumatic disease after childbirth: a population-based cohort study. [PDF]
Scime NV+5 more
europepmc +1 more source
Strain‐Sensitive Thermochromic Smart Electronic Skin for Joint and Spine Healthcare Applications
iStretch, a multifunctional e‐skin integrating durable strain sensing, adaptive heat therapy, and visual feedback, is presented for joint and spine rehabilitation. Featuring a bilayer graphene–liquid metal design, iStretch offers high sensitivity, real‐time responsiveness, and user interactivity, enabling personalized musculoskeletal care through ...
Shicheng Fan+5 more
wiley +1 more source
Altered serum metabolome as an indicator of paraneoplasia or concomitant cancer in patients with rheumatic disease. [PDF]
Gente K+12 more
europepmc +1 more source
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang+12 more
wiley +1 more source
Management and associated outcomes of COVID-19 infection among Ghanaian autoimmune rheumatic disease patients. [PDF]
Dey D+4 more
europepmc +1 more source
A wearable electrochemical biosensor integrated into a smart mouthguard enables the non‐invasive detection of salivary MMP‐8 for early monitoring of periodontal inflammation. Featuring a molecularly imprinted polymer‐based sensing layer, the platform offers high cytokine selectivity and impedance‐driven sensitivity. Combining wireless connectivity with
Sangheon Jeon+10 more
wiley +1 more source
Fatigue patterns surrounding biologic disease-modifying antirheumatic drug injection in patients with an inflammatory rheumatic disease: an ecological momentary assessment study. [PDF]
van Lint JA+5 more
europepmc +1 more source