Results 301 to 310 of about 298,218 (361)

Adipose Tissue Macrophages as Initiators of Exacerbated Periodontitis in Estrogen‐Deficient Environments via the Amplifier Extracellular Vesicles

open access: yesAdvanced Science, EarlyView.
Chronic systemic inflammation, worsened by estrogen deficiency, underlies and exacerbates periodontitis. Proinflammatory macrophages within visceral adipose tissue are hyperactivated due to hyper‐DNA methylation, releasing small extracellular vesicles (sEVs) similar to those of their parent cells.
Danfeng Li   +6 more
wiley   +1 more source

Engineering Neutrophil Vesicles for Synergistic Protection against Ischemia/Reperfusion Injury after Lung Transplant

open access: yesAdvanced Science, EarlyView.
Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan   +10 more
wiley   +1 more source

Strain‐Sensitive Thermochromic Smart Electronic Skin for Joint and Spine Healthcare Applications

open access: yesAdvanced Science, EarlyView.
iStretch, a multifunctional e‐skin integrating durable strain sensing, adaptive heat therapy, and visual feedback, is presented for joint and spine rehabilitation. Featuring a bilayer graphene–liquid metal design, iStretch offers high sensitivity, real‐time responsiveness, and user interactivity, enabling personalized musculoskeletal care through ...
Shicheng Fan   +5 more
wiley   +1 more source

Altered serum metabolome as an indicator of paraneoplasia or concomitant cancer in patients with rheumatic disease. [PDF]

open access: yesAnn Rheum Dis
Gente K   +12 more
europepmc   +1 more source

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

open access: yesAdvanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang   +12 more
wiley   +1 more source

A Wearable Electrochemical Biosensor for Salivary Detection of Periodontal Inflammation Biomarkers: Molecularly Imprinted Polymer Sensor with Deep Learning Integration

open access: yesAdvanced Science, EarlyView.
A wearable electrochemical biosensor integrated into a smart mouthguard enables the non‐invasive detection of salivary MMP‐8 for early monitoring of periodontal inflammation. Featuring a molecularly imprinted polymer‐based sensing layer, the platform offers high cytokine selectivity and impedance‐driven sensitivity. Combining wireless connectivity with
Sangheon Jeon   +10 more
wiley   +1 more source

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