Results 331 to 340 of about 9,604,877 (389)

Correction: Multi-omics integration uncovers key transcriptional regulators in triple-negative breast cancer spatial heterogeneity

Frontiers in Genetics
Ning Zhang, Ning Zhang, Ning Zhang, Ye Zhang, Rui-Fei Yang, Min Tan, Hai-Qing Chu, Abdur Rehman, Lu-Yu Yang, Ya-Yu Li, Fahad M. Alshabrmi, Xin Zhou, Feili Xu, Shou-Ping Gong, Hui-Ling Cao   +14 more
doaj   +1 more source

Carpal tunnel syndrome related to rheumatic disease (Review). [PDF]

Exp Ther Med
Bîrsanu L, Vulpoi GA, Cuciureanu DI, Antal CD, Popescu IR, Turliuc DM.   +5 more
europepmc   +1 more source

Diagnosis, Prognosis, and Drug Target Discovery for Chronic Widespread Pain: A Large Proteogenomic Study

Advanced Science, EarlyView.
Plasma proteomics is leveraged to decode the biological underpinnings of chronic widespread pain. A nested machine learning framework integrates proteomic signatures, prospective outcomes, and Mendelian randomization to uncover 18 causal proteins.
Li Chen, Eoin Kelleher, Ruogu Meng, Duanke Liu, Yuchen Guo, Yunhe Wang, Yaqing Gao, Zhe Huang, Zhu Liang, Shuai Yuan, Chao Zeng, Jun Ma, Yanhui Dong, Anushka Irani, Guanghua Lei, Junqing Xie, Daniel Prieto‐Alhambra   +16 more
wiley   +1 more source

The Association Between Rheumatic Disease Therapies and Cardiovascular Outcomes in People with HIV-A Retrospective Cohort Study. [PDF]

J Clin Med
Titanji BK, Nagatomi S, Gallini JW, Cui X, Hanberg JS, Hsieh E, Marconi VC.   +6 more
europepmc   +1 more source

Constructing Dual‐Atomic Fe─Fe Sites Nanozyme for Targeted Osteoarthritis Therapy through Mitigating Oxidative Stress and Cartilage Degeneration

Advanced Science, EarlyView.
A novel bimetallic nanozyme (Fe2–NCs) with well‐defined Fe–Fe active sites is synthesized through a host–guest coordination strategy, which exhibits an exceptional therapeutic efficacy in osteoarthritis therapy. Experimental and theoretical analyses uncover the intrinsic catalytic mechanism at the atomic level, offering fundamental insights and design ...
Ting Ying, Qi Wang, Dejian Li, Yao Wang, Pengfang Zhang, Chengqing Yi, Rui Zhu   +6 more
wiley   +1 more source

Genetic Association of Juvenile Idiopathic Arthritis With Adult Rheumatic Disease.

JAMA Netw Open
Fan J, Hao J, Fu Y, Liu X, Qu HQ, Glessner JT, Ji D, Liu W, Zheng G, Ding Z, Cui S, Xia Q, Hakonarson H, Wei W, Li J.   +14 more
europepmc   +1 more source

An Analysis of Major Adverse Cardiovascular Events, Other Adverse Events, and Efficacy in Patients with Rheumatic Disease Receiving Targeted Therapy: Experience from a Third-Level Hospital. [PDF]

J Clin Med
Rojas-Giménez M, Muñoz-Reinoso P, Arcila-Durán MD, Moreira-Navarrete V, López MM, Fernández-Alba MD, Ariza-Ariza R, Decan-Bardasz MD, Cruz BH, Toyos FJ, Mendoza DVM, Venegas JJP.   +11 more
europepmc   +1 more source

Type 2 Diabetes‐Associated Phenylacetylglutamine Induces Deleterious Inflammation Cycle in Myeloid Cells through β2 Adrenergic Receptors and Impedes Wound Healing

Advanced Science, EarlyView.
The microbiota‐derived metabolite phenylacetylglutamine (PAGln) is elevated in type 2 diabetes and tightly associated with poor healing in both diabetic and non‐diabetic human patients. PAGln promotes mouse inflammation and impairs healing through a transmissible β2‐adrenergic receptor–mediated trained‐immunity loop.
Lu Huang, Xinran Ye, Chia‐Kang Ho, Ya Gao, Dongsheng Wen, Jiaming Sun, Yuxin Liu, Yangdan Liu, Guoyuan Wang, Yangbai Sun, Jinyan Zhang, Yifan Zhang, Qingfeng Li   +12 more
wiley   +1 more source

Differences in Salivary Cytokinome and Pathogen Load Between Rheumatoid Arthritis and Other Rheumatic Disease Patients. [PDF]

Int J Mol Sci
Korzeniowska A, Daca A, Szarecka M, Bykowska M, Witkowski J, Bryl E.   +5 more
europepmc   +1 more source

Targeted Degradation of sGRP78 Alleviates the Immunosuppressive Tumor Microenvironment

Advanced Science, EarlyView.
Soluble GRP78 (sGRP78) is identified as a novel tumor‐derived soluble factor that induces regulatory T cells (Treg). sGRP78 serves as an excellent serological biomarker for predicting the efficacy of neoadjuvant therapy in breast cancer patients. sGRP78 specifically binds to B cells, inducing the expression of IL‐10 and PD‐L1, thereby promoting Treg ...
Zhenghao Wu, Peng Zheng, Yunxiao Xiao, Qianheng Wang, Xin Pan, Xiaoqi Zhou, Yibing Lv, Junyi Xiao, Yong He, Tao Huang, Ping Lei   +10 more
wiley   +1 more source