Results 81 to 90 of about 9,360,292 (409)

GANT-61 induces cell cycle resting and autophagy by down-regulating RNAP III signal pathway and tRNA-Gly-CCC synthesis to combate chondrosarcoma

Cell Death and Disease, 2023
Chondrosarcoma is ineffective for conventional radiotherapy and chemotherapy with a poor prognosis. Hedgehog (Hh) signal pathway plays a crucial role in tumor growth and progression, which is constitutive activated in chondrosarcoma.
Yifeng Sun, Qiongxuan Fang, Wei Liu, Yi Liu, Chunming Zhang   +4 more
doaj   +1 more source

Treatment adherence and its determinants among the rheumatic fever/rheumatic heart disease patients during COVID 19 pandemic – A cross sectional study from Chandigarh, India

Journal of Family Medicine and Primary Care, 2023
Background: Rheumatic heart disease/Rheumatic fever is a non – communicable disease being a major neglected health problem. Recurrent attacks of rheumatic fever can have catastrophic outcomes, therefore regular administration of antibiotics is ...
Divya Ilanchoorian, J. S. Thakur, Rajesh Vijayvergiya, Ankur K. Jindal, Aravind Gandhi, Vivek Sagar   +5 more
doaj   +1 more source

Discovery and Treatment of Action Potential‐Independent Myotonia in Hyperkalemic Periodic Paralysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hyperkalemic periodic paralysis (hyperKPP) is characterized by attacks of transient weakness. A subset of hyperKPP patients suffers from transient involuntary contraction of muscle (myotonia). The goal of this study was to determine mechanisms causing myotonia in hyperKPP.
Chris Dupont, Adam Deardorff, Murad Nawaz, Andrew A. Voss, Mark M. Rich   +4 more
wiley   +1 more source

Comparison of different intervention thresholds for the treatment of glucocorticoid-induced osteoporosis: a cross-sectional study

BMC Rheumatology
Background Glucocorticoid-induced osteoporosis (GIO) is the most common drug-induced osteoporosis. Early detection and treatment may decrease the fragility fractures. Several GIO guidelines exist, although they vary in recommended intervention thresholds
Kanchalee Puksun, Chatlert Pongchaiyakul, Rattapol Pakchotanon, Pongthorn Narongroeknawin, Pornsawan Leosuthamas, Thunyawarin Arunthanachaikul, Sumapa Chaiamnuay   +6 more
doaj   +1 more source

ABO and Rh blood groups in patients with Lupus and Rheumatoid Arthritis

Caspian Journal of Internal Medicine, 2021
Background: Systemic lupus erythematous (SLE) and rheumatoid arthritis (RA) are autoimmune diseases in which the antigen-antibody system plays an important role.
Amir Nik, Zahra Mirfeizi, Zahra Rezaieyazdi, Mandana Khodashahi, Shahin Danevash, Mohammad Sobhan Sheikh Andalibi, Mahnaz Abbasi, Maryam Sahebari   +7 more
doaj  

Total knee arthroplasty exhibits satisfactory long-term clinical efficacy in the treatment of hemophilia patients with stiff knees

Frontiers in Surgery, 2023
ObjectiveThis study aimed to (1) determine the long-term clinical efficacy of total knee arthroplasty (TKA) in the treatment of hemophilia patients with stiff knessknees, (2) assess the 5- and 10-year prosthesis survival in hemophilia, and (3) determine ...
Yi Liu, Yi Liu, Yi-fan Liu, Yi-fan Liu, Hong-zheng Meng, Tao Sun, Ping Gao, Zhao-zhi Li, Wen-qiang Zhang   +8 more
doaj   +1 more source

Circulating Interleukin‐6 Levels and Timing of Acute Ischemic Stroke Onset

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Intravenous thrombolysis is the most widely available effective ischemic stroke treatment, but is approved only if given within 4.5 h from stroke onset. Many patients are not treated because stroke onset time is unknown. We evaluated the cytokine interleukin 6 (IL‐6) in circulating blood after acute ischemic stroke (AIS).
Robert G. Kowalski, Aurélie Ledreux, John E. Violette, Whitney Paustian, Stefan Sillau, John A. Thompson, Robert T. Neumann, David Ornelas, Andrew A. Monte, Layne Dylla, Adit A. Ginde, Andra M. Farcas, Christina M. Coughlan, William J. Jones, James C. Grotta, Michael W. Graner   +15 more
wiley   +1 more source

Rheumatic diseases and multimorbidity

Terapevticheskii arkhiv, 2015
In the past decade, investigators' undeniable and justified interest has not been fading in comorbidities in the presence of rheumatic diseases. The terms "comorbidity" and "multimorbidity" are frequently and not always consciously used as interinterchangeable, confusing the terminology and accordingly the elaboration of strategies for further ...
E.A. Galushko, E.L. Nasonov, A.V. Gordeev   +2 more
openaire   +4 more sources

Our First Experience on Percutaneous Transvenous Mitral Commissurotomy (PTMC): Case Report [PDF]

, 2005
Rheumatic heart disease remains a significant healt problem especially in devaloping countries. In rheumatic heart disease, mitral valve is affected in nearly all cases; mitral stenosis is the most common lesion.
Aziz Karabulut, Aziz Karadede, Kenan İltümür, Nizamettin Toprak   +3 more
core  

Confidence amongst multidisciplinary professionals in managing paediatric rheumatic disease in Australia [PDF]

, 2018
Objective. Interprofessional collaboration is a crucial component of care for children with rheumatic disease. Interprofessional care, when delivered appropriately, prevents disability and improves long-term prognosis in this vulnerable group.
Cassidy, Samuel, Coda, Andrea, Grech, Debra, Hawke, Fiona, Hendry, Gordon, Jones, Julie, Singh-Grewal, Davinder, West, Kerry   +7 more
core   +2 more sources