Results 201 to 210 of about 268,778 (321)

The Impact of Menopause on Autoimmune and Rheumatic Diseases. [PDF]

Clin Rev Allergy Immunol
Motta F, Di Simone N, Selmi C.
europepmc   +1 more source

Serum Cholesterol in Rheumatic Diseases [PDF]

, 1963
Margery London, K. D. Muirden, J. V. Hewitt   +2 more
openalex   +1 more source

Climate und Rheumatic Diseases [PDF]

, 1992
Baenkler, Hanns-Wolf, Schuh, Angela, Senn, E.   +2 more
core  

Mechanical Load‐Induced Upregulation of Talin2 through Non‐Canonical Deubiquitination of OTUB1 Drives Facet Joint Osteoarthritis Pathogenesis

Advanced Science, EarlyView.
Facet joint osteoarthritis (FJOA), prevalent in the elderly, involves Talin2 upregulation promoting ECM degradation while suppressing synthesis. Mechanical load stabilizes Talin2 via OTUB1‐mediated non‐canonical deubiquitination, driving CCL2 expression that recruits immune cells, exacerbating inflammatory joint degeneration.
Yizhen Huang, Heng Sun, Haojie Chen, Xiangpeng Wang, Junduo Zhao, Yang Jiao, Hongyi Zhou, Haoyu Cai, Jiafeng Dai, Xuan Huang, Weiyun Chen, Jianxiong Shen   +11 more
wiley   +1 more source

Protocol for the MERINO study: A randomized placebo-controlled trial assessing the efficacy, safety, and cost-effectiveness of methotrexate in people with erosive hand osteoarthritis

Osteoarthritis and Cartilage Open
Objective: Previous studies on the efficacy of methotrexate in people with hand osteoarthritis (OA) have shown conflicting results. The MERINO trial aims to investigate the efficacy and safety of methotrexate in people with painful inflammatory erosive ...
Alexander Mathiessen, Line Gaundal, Joseph Sexton, Dag Sjølie, Pernille Steen Pettersen, Barbara Slatkowsky-Christensen, Ida Kristin Haugen   +6 more
doaj  

Cardio-Rheumatic Diseases: Inflammasomes Behaving Badly. [PDF]

Int J Mol Sci
Issa F, Abdulla M, Retnowati FD, Al-Khawaga H, Alhiraky H, Al-Harbi KM, Al-Haidose A, Maayah ZH, Abdallah AM.   +8 more
europepmc   +1 more source

Bacterial Capture‐Killing Capsules with Remodeling Bone Immune Microenvironment for the Effective Treatment of Osteomyelitis

Advanced Science, EarlyView.
The PC‐O@TOB capsules are designed to exhibit bactericidal effects, regulate the bone immune microenvironment by promoting M2 macrophage polarization, eliminate excessive ROS, and enhance bone regeneration, providing a novel multi‐dimensional approach for the treatment of osteomyelitis.
Dong Yang, Chang Shu, Chengwei Xu, Xingjie Zan, Shaoyin Wei, Chenglong Wang, Lianxin Li   +6 more
wiley   +1 more source

Sarcopenia in Rheumatic Diseases: A Hidden Issue of Concern. [PDF]

Diseases
Pardali EC, Klonizakis M, Goulis DG, Papadopoulou SK, Cholevas C, Giaginis C, Tsigalou C, Bogdanos DP, Grammatikopoulou MG.   +8 more
europepmc   +1 more source

Plasma cortisol response to synacthen (beta-1-24 Ciba) at different times of the day in patients with rheumatic diseases. [PDF]

, 1967
Peter McGill, W. R. Greig, M C Browning, J A Boyle   +3 more
openalex   +1 more source

Therapeutic Potential of Lipid Nanoparticle‐Encapsulated CD19‐Targeting mRNAs in Lupus and Rheumatoid Arthritis

Advanced Science, EarlyView.
This study develops lipid nanoparticle‐encapsulated mRNA‐encoding antibodies (mRNab‐LNPs) targeting CD19, demonstrating robust anti‐CD19 antibody production in vivo. Intramuscular injection of mRNab‐LNPs reduces CD19+ B and plasma cells in lupus and rheumatoid arthritis mice, significantly alleviating histopathological changes and tissue injuries of ...
Chipeng Guo, Yingsen Tang, Ling Zeng, Xiaomei You, Siweier Luo, Yufei Du, Le Wang, Liangchun Wang, Jianchuan Wang, Jinjin Chen, Yiming Zhou   +10 more
wiley   +1 more source