Results 241 to 250 of about 10,740,045 (356)

Editorial for Recent Advances in Autoimmune Rheumatic Diseases: 2nd Edition. [PDF]

Medicina (Kaunas)
Mieliauskaitė D.
europepmc   +1 more source

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

Advanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang, Siqi Guo, Jing Li, Qianqian Huang, Jing Ning, Binbin Xia, Xun Lv, Xiang Liu, Zeyu Gao, Jine Li, Longchao Liu, Moshi Song, Jun Wang   +12 more
wiley   +1 more source

In utero and early life exposures to smoking are associated with systemic autoimmune rheumatic diseases. [PDF]

Semin Arthritis Rheum
Ohnishi T, Zhao M, Shi M, Volochayev R, Jackson SH, Jansen A, Bayat N, Farhadi PN, Sarkar K, Flegel WA, Parks CG, Weinberg CR, Miller FW, Schiffenbauer A, Rider LG.   +14 more
europepmc   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Interstitial lung disease in systemic autoimmune rheumatic diseases: radiologic and histologic correlations. [PDF]

Rheumatol Adv Pract
Pye A, Jalaledin DS, Chang A, Saleh N, AlHajeri S, Daviault B, Shah A, Hoa S, Yu A, Levy RD, Wilson JM, Poirier CD, Choi J, Yee J, Landon Cardinal O, Kim H, Huang K.   +16 more
europepmc   +1 more source

ZMAT1 Promotes Osteoclastogenesis Through TRIM46 Mediated YAP1 Degradation and Inhibits Osteoblastogenesis

Advanced Science, EarlyView.
Zmat1 deficiency mitigates pathological bone loss by impairing osteoclastogenesis and promoting osteoblastogenesis. Mechanistically, in osteoclasts, Zmat1 loss relieves transcriptional repression of the E3 ligase TRIM46, promoting YAP1 degradation and inhibiting osteoclastogenic genes.
Xinyu Chang, Yijin Hou, Likun Cui, Huiqi Yu, Rong Liu, Junhao Sui, Zhong Zheng, Lu Liu, Jie Chen, Mengchen Chen, Chen Ding, Shuogui Xu, Sheng Xu, Hao Zhang   +13 more
wiley   +1 more source

Mucosal-Associated Invariant T Cells in Rheumatic Diseases. [PDF]

Arthritis Rheumatol
Lesturgie-Talarek M, Gonzalez V, Beaudoin L, Sénot N, Miceli-Richard C, Allanore Y, Lehuen A, Avouac J.   +7 more
europepmc   +1 more source

MCV/Q, Medical College of Virginia Quarterly, Vol. 10 No. 2 [PDF]

, 1974

core   +1 more source

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source