Results 171 to 180 of about 223,917 (311)

Demographic, Lifestyle, and Serologic Risk Factors for Rheumatoid Arthritis (RA)-associated Bronchiectasis: Role of RA-related Autoantibodies. [PDF]

J Rheumatol, 2022
McDermott G, Gill R, Gagne S, Byrne S, Huang W, Wang X, Prisco LC, Zaccardelli A, Martin LW, Masto L, Kronzer VL, Shadick N, Dellaripa PF, Doyle TJ, Sparks JA.   +14 more
europepmc   +1 more source

5. Rheumatoid Arthritis (RA)

Nihon Naika Gakkai Zasshi, 2010
Hitoshi Tomiyasu, Toshio Tomiyasu, Fumihito Yoshii   +2 more
openaire   +2 more sources

Sjögren Disease—B Cells at the Brink: From Autoimmunity to Lymphomagenesis and the Rise of Novel B Cell–Targeted Therapies

Arthritis &Rheumatology, EarlyView.
Sjögren disease (SjD) is a common systemic autoimmune disorder characterized by inflammation of the exocrine glands, resulting in dryness. Patients frequently exhibit extraglandular manifestations affecting various organ systems. To date, there are no US Food and Drug Administration (FDA)‐approved disease‐modifying therapies for SjD. In this review, we
Rachael A. Gordon, Sara S. McCoy
wiley   +1 more source

Association between serum bone biomarker levels and therapeutic response to abatacept in patients with rheumatoid arthritis (RA): a multicenter, prospective, and observational RA ultrasound cohort study in Japan. [PDF]

BMC Musculoskelet Disord, 2021
Kawashiri SY, Endo Y, Nishino A, Okamoto M, Tsuji S, Takatani A, Shimizu T, Sumiyoshi R, Koga T, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Aramaki T, Ueki Y, Yoshitama T, Eiraku N, Matsuoka N, Okada A, Fujikawa K, Hamada H, Nagano S, Tada Y, Kawakami A.   +24 more
europepmc   +1 more source

Effects of curcumin and Curcuma longa extract on inflammatory biomarkers in patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE): a systematic review and meta-analysis of randomized controlled trials. [PDF]

Inflamm Res
Liu AJ, Wu PC, Chen YP, Chu HT, Chang HH.   +4 more
europepmc   +1 more source

Distinct HLA Associations for Antibody Multireactivity With Citrulline‐Containing Type II Collagen Epitopes Versus More Limited Antibody Reactivity With Citrulline‐Containing IgG Epitopes in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Objective Anticitrullinated protein antibodies (ACPAs) in rheumatoid arthritis (RA) can be promiscuous, with cross‐reactive binding to many antigens containing short motifs, or private with little cross‐reactivity. Also, ACPA reactivity patterns differ among patients with RA, including for motif‐containing epitopes in important self‐antigens like ...
S. Janna Bashar, Courtney B. Myhr, Adam H. Titi, Zihao Zheng, Miriam A. Shelef   +4 more
wiley   +1 more source

A Multifaceted Computational Approach to Identify PAD4 Inhibitors for the Treatment of Rheumatoid Arthritis (RA). [PDF]

Metabolites
Alturki MS, Gomaa MS, Tawfeeq N, Al Khzem AH, Shaik MB, Alshaikh Jafar M, Alsamen M, Al Nahab H, Al-Eid M, Almutawah A, Rants'o TA, Ayil KAG, Almaghrabi M.   +12 more
europepmc   +1 more source

Identification of histone deacetylase inhibitor targeting type I interferon and B‐cell abnormalities in systemic lupus erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is characterized by increased type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama, Hachiro Konaka, Yasuhiro Kato, Takayuki Shibahara, Chisato Nishizawa, Kohei Tsujimoto, JeongHoon Park, Eri Itotagawa, Tatsunori Jo, Masayuki Nishide, Sumiyuki Nishida, Yoshihito Shima, Masashi Narazaki, Wataru Aoki, Ken J Ishii, Hyota Takamatsu, Atsushi Kumanogoh   +16 more
wiley   +1 more source

Correction to: Biologic monotherapy in the biologic naïve patient with rheumatoid arthritis (RA): results from an observational study. [PDF]

Rheumatol Int, 2020
Benson R, Zhao SS, Goodson N, Abernethy R, Mewar D, Barnes T.   +5 more
europepmc   +1 more source

Lifelong evolution of autoreactive plasma cell numbers, affinity and anatomical location in arthritic K/BxN mice

Arthritis &Rheumatology, Accepted Article.
Objective The spontaneous K/BxN mouse model of rheumatoid arthritis has been used extensively to study chronic inflammation, contribution of immune cells, and the primordial role of autoreactive antibodies in disease initiation and severity. Only the ubiquitous enzyme glucose‐6‐phosphate isomerase (GPI) is the target of IgG autoantibodies secreted by ...
Thibault Vanhoucke, Carlos Castrillon, Odile Richard‐Le Goff, Angga Perima, Matteo Broketa, Andrew D. Griffiths, Patrick England, François Huetz, Pierre Bruhns   +8 more
wiley   +1 more source