Results 71 to 80 of about 223,917 (311)

Identification of mitophagy-related biomarkers in human rheumatoid arthritis using machine learning models

open access: yesArtificial Cells, Nanomedicine, and Biotechnology
Rheumatoid arthritis (RA) is a systemic immune-mediated disease characterized by synovitis and joint cartilage destruction. Although many studies have shown that mitophagy is crucial in the development of bone metabolism disorders, its exact function in ...
Jiayi Chen   +4 more
doaj   +1 more source

Use of antikeratin antibodies to distinguish between rheumatoid arthritis and polyarthritis associated with hepatitis C infection

open access: yesReumatismo, 2001
Objective: To investigate whether antikeratin antibodies (AKA) could be usefull in the differential diagnosis of patients with rheumatoid arthritis (RA) compared to patients with hepatitis C virus (HCV) associated polyarthritis, who are seropositive for ...
A. Kessel   +4 more
doaj   +1 more source

Immunopathogenesis of rheumatoid arthritis [PDF]

open access: yes, 2017
Rheumatoid arthritis (RA) is the most common inflammatory arthropathy. The majority of evidence, derived from genetics, tissue analyses, models, and clinical studies, points to an immune-mediated etiology associated with stromal tissue dysregulation that
Ahmed   +115 more
core   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

open access: yesArthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti   +19 more
wiley   +1 more source

The study of tempromandibular joint disorders and anti-cyclic citrullinated peptide antibodies in serum and saliva of patients with rheumatoid arthritis

open access: yesJournal of Baghdad College of Dentistry, 2014
Background: Rheumatoid arthritis is an autoimmune disease that affects mainly the synovial membranes and articular structures and is characterized by chronic, systemic inflammation involving multiple joints.Being a synovial joint, the Temporomandibular ...
Raya M Khidhir, Raja H Al-Jubouri
doaj  

Epigenome association study for DNA methylation biomarkers in buccal and monocyte cells for female rheumatoid arthritis

open access: yesScientific Reports, 2021
Genetics (i.e., mutations) has been assumed to be the major factor in rheumatoid arthritis (RA) etiology, but accounts for a minority of the variance in disease risk for RA.
Gary Craig   +5 more
doaj   +1 more source

Podiatry services for patients with arthritis: an unmet need [PDF]

open access: yes, 2010
Foot problems are extremely common in patients with rheumatoid arthritis (RA). There is ample evidence that foot pain, either alone or as a comorbidity, contributes significantly to disability.
Chapman, J   +4 more
core   +1 more source

Mucosa-Environment Interactions in the Pathogenesis of Rheumatoid Arthritis [PDF]

open access: yes, 2019
Mucosal surfaces play a central role in the pathogenesis of rheumatoid arthritis (RA). Several risk factors, such as cigarette smoking, environmental pollution, and periodontitis interact with the host at the mucosal level, triggering immune system ...
Conti, Fabrizio   +5 more
core   +1 more source

A Qualitative Analysis of Patient Perspectives and Preferences in Lupus Management to Guide Lupus Guidelines Development

open access: yesArthritis Care &Research, EarlyView.
Objective A patient‐centered approach for chronic disease management, including systemic lupus erythematosus (SLE), aligns treatment with patients’ values and preferences, leading to improved outcomes. This paper summarizes how patient experiences, perspectives, and priorities informed the American College of Rheumatology (ACR) 2024 Lupus Nephritis (LN)
Shivani Garg   +20 more
wiley   +1 more source

Echocardiography in Rheumatoid Arthritis (RA) [PDF]

open access: yes, 2011
The results of numerous clinical studies confirm the presence of cardiac abnormalities in patients with rheumatoid arthritis. Their authors emphasize the utility of echocardiography in detecting heart muscle damage, pericardial involvement and valvular heart disease in RA. Bacon and Gibson, using one-dimentional imaging mode, found mitral valve changes
openaire   +3 more sources

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